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Table 2 Analysis of prognostic factors related to local control after RT

From: High-dose carbon-ion based radiotherapy of primary and recurrent sacrococcygeal chordomas: long-term clinical results of a single particle therapy center

  Univariate testing Multivariate testing
Parameter p-value HR 95% CI p-value HR 95% CI
EQD2 (Gy) 0.13 0.95 0.90–1.01 0.14 0.96 0.90–1.02
Therapy situation (primary vs. recurrent tumor) <  0.001 4.25 1.99–9.09 <  0.001 4.55 2.06–10.08
GTV (ml) 0.59 1.21 0.60–2.46 0.16 1.70 0.81–3.57
Treatment approach (C12 vs. C12 + Ph) 0.49 1.29 0.63–2.64 NA NA NA
  1. Abbreviations: HR Hazard ratio, 95% CI 95% confidence interval, EQD2 Cumulative equivalent radiation dose, GTV Gross tumor volume, C12 Carbon ions, Ph Photons, NA Not analyzed