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Table 1 Patients’ properties

From: High-dose carbon-ion based radiotherapy of primary and recurrent sacrococcygeal chordomas: long-term clinical results of a single particle therapy center

Characteristics Value %
Age (years)
 Median 61  
 Range 34–84  
Gender (n)
 Female 22 32.4
 Male 46 67.6
Resection status (n)
 Biopsy 28 41.2
 R2 26 38.2
 R0/1 14 20.6
Treatment (n)
 Primary 52 76.5
 Recurrent 16 23.5
Most cranial level of tumor (n)
 L4/5 7 10.3
 S1 12 17.7
 S2 23 33.8
 S3 14 20.6
 S4 5 7.4
 S5 4 5.9
 Os coccygeum 3 4.4
GTV (ml)
 Median 182  
 Range 0–1727  
CTV1 (ml)
 Median 263  
 Range 0–1743  
CTV2 (ml)
 Median 938  
 Range 60–2577  
PTV1 (ml)
 Median 414  
 Range 0–2325  
PTV2 (ml)
 Median 1109  
 Range 84–3138  
Radiation dose ED2Gy   
Carbon ion only: (α/β = 2)   
 60 Gy/3 Gy (RBE) 75.0 Gy 16 23.5
 63 Gy/3 Gy (RBE) 78.8 Gy 2 2.9
 66 Gy/3 Gy (RBE) 82.5 Gy 14 20.6
 64 Gy/4 Gy (RBE) 96.0 Gy 14 20.6
IMRT + carbon ion boost
 50 Gy/2 Gy + 15 Gy/3 Gy (RBE) 68.8 Gy 1 1.5
 50 Gy/2 Gy + 18 Gy/3 Gy (RBE) 74.5 Gy 1 1.5
 50 Gy/2 Gy + 24 Gy/3 Gy (RBE) 80.0 Gy 20 29.4
  1. Abbreviations: GTV Gross tumor volume, CTV1 Clinical target volume (Boost plan), CTV2 Clinical target volume (primary plan), RBE Relative biological effectiveness, IMRT Intensity-modulated radiotherapy