Skip to main content

Table 3 Impact of TTI on locoregional control and index cancer-specific hazard (N = 197 patients with 207 tumors): a multivariate analysis

From: Impact of delays in radiotherapy of head and neck cancer on outcome

Parameter HR 95% CI P-value
Locoregional control
 TNM (III vs. I-II) 0.843 0.369–1.925 0.685
 TNM (IV vs. I-II) 2.320 1.211–4.444 0.011
 Age 0.976 0.950–1.002 0.075
 TTI 1.012 0.998–1.027 0.094
 Gender 0.501 0.201–1.249 0.138
 Therapy (CCT vs. RT) 0.768 0.444–1.328 0.344
Cause specific hazard
 TNM (III vs. I-II) 3.203 1.286–7.976 0.012
 TNM (IV vs. I-II) 13.223 6.007–29.108 < 0.001
 Age 0.985 0.965–1.005 0.133
 TTI 1.001 0.990–1.012 0.844
 Gender 0.907 0.529–1.556 0.724
 Therapy (CCT vs. RT) 0.534 0.369–0.774 0.001
  1. CI Confidence interval; TTI Time to treatment intervention;
  2. CCT Concurrent chemoradiotherapy; RT Radiotherapy