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Table 2 Effect of covariates on locoregional control and index cancer-specific hazard (N = 197 patients with 207 tumors): an univariate analysis

From: Impact of delays in radiotherapy of head and neck cancer on outcome

Parameter

HR

95% CI

P-value

Locoregional control

 TNM (III vs. I-II)

0.855

0.378–1.934

0.706

 TNM (IV vs. I-II)

2.265

1.276–4.021

0.005

 Age

0.969

0.944–0.994

0.015

 TTI

1.013

0.997–1.028

0.104

 Gender

0.476

0.191–1.183

0.110

Therap (CCT vs. RT)

1.370

0.857–2.189

0.188

Cause specific hazard

 TNM (III vs. I-II)

0.855

0.378–1.934

0.026

 TNM (IV vs. I-II)

2.265

1.276–4.021

< 0.001

 Age

0.979

0.961–0.997

0.024

 TTI

1.003

0.991–1.014

0.631

 Gender

0.827

0.483–1.416

0.489

 Therapy (CCT vs. RT)

1.234

0.877–1.736

0.228

  1. CI Confidence interval; TTI Time to treatment intervention;
  2. CCT Concurrent chemoradiotherapy; RT Radiotherapy