Table 1 Basic information of included studies
First author | Region | Average or median age | n | Gliomas grade(n) | Instrument Type and Field Strength | Technique | Diagnostic parameters | QUADAS-2 score |
|---|---|---|---|---|---|---|---|---|
Arisawa 2018 [16] | Japan | 50(19–74) | 34 | I + II(15),III + IV(19) | GE 3.0 T | ASL,DSC | rCBF, rCBV | 12 |
Cebeci 2014 [17] | Turkey | 47 ± 14 | 33 | I + II(13),III + IV(20) | Philips 3.0 T | ASL | rCBF | 13 |
Fudaba 2014 [18] | Japan | 59.8 ± 16.8 | 32 | II(9),III(8),IV(15) | Siemens 3.0 T | ASL | rCBF | 13 |
Furtner 2014 [19] | Australia | 54 ± 17 | 33 | II(7),III(7),IV(19) | Siemens 3.0 T | ASL | rCBF | 12 |
Jiang J 2014 [20] | China | 42.7 ± 15.3 | 23 | I + II(10),III + IV(13) | GE 3.0 T | ASL | rCBF | 12 |
Kim 2008 [21] | South Korea | 43(19–74) | 61 | I + II(26),III + IV(35) | GE 1.5 T | ASL | rCBF | 11 |
Liao H 2016 [22] | China | 40.5 | 41 | I + II(20),III + IV(21) | GE 3.0 T | ASL | rCBF | 11 |
Liu 2014 [23] | China | 8–75 | 38 | I(5),II(17),III(7),IV(9) | GE 3.0 T | ASL | rCBF | 12 |
Ma 2017 [24] | China | 46 ± 18 | 50 | I + II(27),III + IV(23) | GE 3.0 T | ASL,DSC | rCBF, rCBV | 11 |
Qiao F 2015 [25] | China | 50(26–72) | 28 | I + II(11),III + IV(17) | GE 3.0 T | ASL | rCBF | 10 |
Roy 2013 [7] | India | 43 | 64 | I(3),II(23),III(9),IV(29) | GE 3.0 T | ASL | rCBF | 11 |
Shen 2016 [26] | China | 42 | 52 | I + II(25),III + IV(27) | GE 3.0 T | ASL | rCBF | 9 |
Tian Q 2015 [27] | China | 47(19–76) | 45 | I + II(19),III + IV(26) | GE 3.0 T | ASL | rCBF | 12 |
Wang N 2019 [28] | China | 48(23–81) | 53 | I(1),II(15),III(13),IV(24) | GE 3.0 T | ASL | rCBF | 10 |
Morana 2018 [29] | Italy | 9(2–17) | 37 | I(8),II(14),III(6),IV(9) | Philips 1.5 T | ASL,DSC | rCBF, rCBV | 10 |
Wolf 2005 [30] | USA | 50 ± 12 | 26 | I + II(7),III + IV(19) | Siemens 3.0 T | ASL | rCBF | 10 |
Xiao 2015 [31] | China | 43.3(6–74) | 43 | I + II(19),III + IV(24) | GE 3.0 T | ASL | rCBF | 11 |
Yang 2016 [32] | China | 51 ± 15.34 | 43 | II(15),III(15),IV(13) | Siemens 3.0 T | ASL | rCBF | 12 |
Zeng 2017 [33] | China | 50 ± 13 | 58 | II(13),III(17),IV(28) | GE 3.0 T | ASL | rCBF | 11 |
Zhao J 2016 [34] | China | 42(15–64) | 18 | I + II(8),III + IV(10) | GE 3.0 T | ASL | rCBF | 9 |
Van Cauter 2014 [35] | Belgium | 55 | 31/ 35 | I + II(12),III + IV(19)-DSC I + II(13),III + IV(22)-DKI | Philips 3.0 T | DSC ,DKI | rCBV, MK | 9 |
Awasthi 2012 [36] | India | 16–65 | 76 | I + II(21),III + IV(55) | GE 1.5 T | DSC | rCBV | 12 |
Boxerman 2016 [37] | USA | 52(19–80) | 43 | II(11),III(9),IV(23) | GE 1.5 T | DSC | rCBV | 12 |
Brendle 2018 [38] | Germany | 23–79 | 41 | I + II(24),III + IV(17) | Siemens 3.0 T | DSC | rCBV | 14 |
Catalaa 2006 [39] | USA | 23–78 | 17 | II(8),III(9) | GE 1.5 T | DSC | rCBV | 11 |
Cuccarini 2016 [40] | Italy | 39.6 ± 12.6 | 68 | I + II(42),III + IV(26) | Siemens 1.5 T | DSC | rCBV | 12 |
Dallery 2017 [41] | France | 9.4 (2.1–17.9) | 30 | I(7),II(4),III(7),IV(12) | GE 3.0 T | DSC | rCBV | 11 |
Falk 2014 [42] | Sweden | 22–79 | 25 | II(18),III(7) | Philips 3.0 T | DSC | rCBV | 10 |
Fatima 2014 [43] | Brazil | 36.23± 16.95 | 38 | I + II(16),III + IV(22) | GE 1.5 T | DSC | rCBV | 13 |
Hilario 2012 [44] | Spain | 23–79 | 162 | II(32),III(29),IV(101) | GE 3.0 T | DSC | rCBV | 10 |
Huang 2015 [45] | China | 45(17–72) | 35 | I(2),II(12),III(9),IV(12) | Siemens 3.0 T | DSC | rCBV | 9 |
Kim 2013 [46] | South Korea | 35 | 63 | II(9),III(16),IV(38) | Siemens 3.0 T | DSC | rCBV | 9 |
Law 2006 [47] | USA | 42(4–85) | 73 | II(31),III(16),IV(26) | Siemens 3.0 T | DSC | rCBV | 11 |
Wang M 2011 [48] | China | 42.9 ± 14.7 | 23 | I(1),II(5),III(8),IV(9) | Siemens 3.0 T | ASL,DSC | rCBF, rCBV | 9 |
Nguyen 2016 [49] | Canada | 54 | 43 | I + II(10),III + IV(33) | Siemens 3.0 T | DSC | rCBV | 12 |
Santarosa 2016 [8] | Italy | 55.4 (22–79) | 26 | II(9),III(4),IV(13) | Philips 3.0 T | DSC | rCBV | 9 |
Server 2011 [50] | Norway | 57.73± 12.95 | 79 | II(18),III(14),IV(47) | GE 3.0 T | DSC | rCBV | 10 |
Togao 2017 [51] | Japan | 14–75 | 34 | I + II(20),III + IV(14) | Philips 3.0 T | DSC | rCBV | 12 |
Wang X 2016 [52] | China | 41 ± 15 | 37 | I + II(14),III + IV(23) | GE 3.0 T | ASL,DKI | rCBF, MK | 10 |
Falk Delgado 2017 [53] | Sweden | 48 ± 15 | 35 | II(23),III(12) | Philips 3.0 T | DKI | MK | 10 |
Gao A 2017 [54] | China | 48.66± 13.42 | 34 | II(21),III(13) | Siemens 3.0 T | DKI | MK | 10 |
Hempel 2017 [55] | USA | 50 ± 14 | 50 | II(25),III(15),IV(10) | Siemens 3.0 T | DKI | MK | 11 |
Jiang 2015 [56] | China | 41 ± 14 | 74 | I(3),II(31),III(19),IV(21) | GE 3.0 T | DKI | MK | 10 |
Li 2016 [57] | China | 47 | 37 | I + II(16),III + IV(21) | Siemens 3.0 T | DKI | MK | 9 |
Lin 2018 [58] | China | 42–75 | 96 | I + II(84),III + IV(12) | GE 3.0 T | DKI | MK | 10 |
Maximov 2017 [59] | Germany | 18–59 | 24 | II(8),III(8),IV(8) | GE 3.0 T | DKI | MK | 11 |
Qi 2018 [60] | China | 11–67 | 39 | I + II(13),III + IV(26) | Siemens 3.0 T | DKI | MK | 9 |
Raab 2010 [61] | Germany | 56 | 18 | II(5),III(13) | Siemens 3.0 T | DKI | MK | 11 |
Raja 2016 [62] | Germany | 35 | 18 | II(9),III(9) | Philips 3.0 T | DKI | MK | 12 |
Tan 2016 [63] | China | 50 | 60 | I + II(25),III + IV(35) | GE 3.0 T | DKI | MK | 11 |
Tietze 2015 [64] | Denmark | 42 | 34 | II(12),III(7),IV(15) | Siemens 3.0 T | DKI | MK | 10 |
Zheng G 2014 [65] | China | 40.3 ± 19.5 | 21 | I(2),II(3),III(7),IV(9) | GE 3.0 T | ASL,DSC | rCBF, rCBV | 10 |
Wang Y 2017 [66] | China | 47.5 (25–75) | 32 | I + II(14),III + IV(18) | Siemens 3.0 T | DKI | MK | 10 |
Zhao 2019 [67] | China | 25–75 | 52 | II(24),III(8),IV(20) | Siemens 3.0 T | DKI | MK | 12 |