Table 2 Baseline patient characteristics of patients by treatment subgroups
Treatment subgroup | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Adjuvant hormonal therapy | Yes | Yes | No | ||||||
Adjuvant chemotherapy | No | Yes | Yes or No | ||||||
Characteristics | RS < 25 | RS ≥ 25 | P | RS < 25 | RS ≥ 25 | P | RS < 25 | RS ≥ 25 | P |
Total, n (%) | 1125 (94) | 74 (6) | – | 241 (51) | 229 (49) | – | 63 (71) | 26 (29) | – |
Age, median (interquartile range) | 54 (48–62) | 65 (54–70) | < 0.001 | 49 (44–56) | 54 (46–62) | < 0.001 | 52 (46–63) | 53 (45–63) | 0.96 |
Stage, n (%) | 0.18 | 0.09 | 0.15 | ||||||
I | 799 (71) | 58 (78) | 153 (63) | 162 (71) | 44 (70) | 14 (54) | |||
II | 326 (29) | 16 (22) | 88 (37) | 67 (29) | 19 (30) | 12 (46) | |||
Surgery type, n (%) | 0.03 | 0.37 | 0.81 | ||||||
Breast-conserving surgery | 812 (72) | 62 (84) | 159 (66) | 160 (70) | 42 (67) | 18 (69) | |||
Mastectomy | 313 (28) | 12 (16) | 82 (34) | 69 (30) | 21 (33) | 8 (31) | |||
Postoperative radiation, n (%) | 0.84 | 0.86 | 0.59 | ||||||
No | 301 (27) | 19 (26) | 66 (27) | 61 (27) | 30 (52) | 14 (46) | |||
Yes | 824 (73) | 55 (74) | 175 (73) | 168 (73) | 33 (48) | 12 (54) | |||
Number of events, n | – | – | – | ||||||
iLRR | 16 | 3 | 1 | 1 | 1 | 0 | |||
DM without iLRR | 9 | 2 | 2 | 6 | 0 | 1 | |||
Death without iLRR or DM | 7 | 3 | 0 | 2 | 0 | 1 | |||