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Table 1 Patient characteristics (N = 11)

From: Clinical impact of Hypofractionated carbon ion radiotherapy on locally advanced hepatocellular carcinoma

Characteristics

 

Age, years, median (range)

76 (57–86)

Tumor size, mm, median (range)

53 (27–119)

Sex, number

 Male:Female

9:2

Etiology

 Hepatitis C virus antibody positive

4

 Hepatitis B surface antigen positive

3

 NASH/NAFLD

2

 Unidentified

2

Prior treatment of C-ion RT

 TACE

6

 TACE and RFA

2

 TACE and hepatic artery infusion chemotherapy

2

 Treatment naïve

1

Site of direct invasion

 Major branch of the portal vein

3

 Major branch of the hepatic vein

5

 Both major branches of the portal vein and the hepatic vein

3

Child-Pugh class

 A:B

10:1

Barcelona Clinic Liver Classification Stage

 A:B:C

2:0:9

Albumin-Bilirubin Grade

1:2a:2b:3

3:2:5:1

Pretreatment AFP, IU/ml

  < 200

6

 200–400

2

  > 400

3

Indocyanine green retention rate at 15 min

  < 15%

5

 15–30%

4

  > 30%

2

 Median (range)

15.9 (4.9–108.7)

  1. Abbreviations: AFP alpha-fetoprotein, C-ion RT carbon ion radiotherapy, NASH/NAFLD non-alcoholic fatty liver disease/non-alcoholic steatohepatitis, RFA percutaneous radiofrequency ablation, TACE transarterial chemoembolization