Table 1 Patient characteristics of 80 NSCLC patients with LM
Variable | N (%) |
|---|---|
Total | 80 (100.0) |
Gender | |
 Male | 44 (54.1) |
 Female | 36 (45.9) |
Age, years | |
 Median (range) | 53.5 (30–78) |
Histology | |
 Adenocarcinoma | 73 (91.3) |
 Squamous | 7 (8.8) |
Initial stage | |
 I-III | 25 (31.3) |
 IV | 55 (68.8) |
Previous lines of systematic therapy | |
 0 | 19 (23.8) |
 1 | 29 (36.3) |
 2 | 19 (23.8) |
 ≥ 3 | 13 (16.3) |
Previous EGFR TKI prior to LM | 46 (57.5) |
EGFR mutation | |
 EGFR 19del | 25 (31.3) |
 EGFR L858R | 18 (22.5) |
 EGFR T790M | 5 (6.3) |
 EGFR 20INS | 1 (1.3) |
 Wild-type | 31 (38.8) |