Table 4 Biologically effective dose to the OARs from initial primary treatment, and salvage HyperArc or RapidArc SBRT for recurrent nasopharyngeal cancer patients
Parameters | Primary treatment Mean (SEM) | Salvage HA Mean (SEM) | Salvage RA Mean (SEM) | p value | Cumulative dose (P + HA) Mean (SEM) | Cumulative dose (P + RA) Mean (SEM) | p value |
|---|---|---|---|---|---|---|---|
Organs at risk (Gy3) | |||||||
Spinal cord | 58.14 (1.91) | 4.80 (1.99) | 4.62 (2.02) | 0.878 | 63.33 (2.77) | 61.57 (1.92) | 0.173 |
Brainstem | 67.73 (2.39) | 6.65 (3.02) | 6.91 (3.08) | 0.203 | 72.18 (2.15) | 72.38 (1.83) | 0.260 |
Brain | 114.83 (2.39) | 68.78 (12.23) | 77.03 (11.77) | 0.028* | 176.85 (12.20) | 185.94 (11.62) | 0.038* |
Temporal lobe | 115.66 (2.09) | 52.69 (11.99) | 54.05 (12.43) | 0.799 | 159.90 (9.94) | 161.24 (9.44) | 0.767 |
Chiasma | 13.10 (3.12) | 3.25 (1.24) | 1.08 (0.14) | 0.013* | 16.56 (3.25) | 14.10 (3.08) | 0.008* |
Optic nerve_right | 27.86 (6.47) | 2.80 (0.94) | 2.27 (1.50) | 0.074 | 30.08 (6.30) | 28.64 (6.46) | 0.008* |
Optic nerve_left | 29.12 (6.86) | 2.25 (0.87) | 1.12 (0.34) | 0.005* | 31.16 (6.63) | 29.90 (6.85) | 0.008* |
Eye_right | 22.87 (7.20) | 1.45 (0.66) | 2.62 (1.80) | 0.959 | 23.67 (7.18) | 23.70 (7.28) | 0.515 |
Eye_left | 20.08 (6.37) | 1.81 (0.80) | 2.51 (1.82) | 0.203 | 21.12 (6.41) | 20.77 (6.38) | 0.038* |