Table 6 Grade 3–4 acute adverse events in 170 paired patients with stage T3-4N1 NPC
Variables | NCT + CCRT group (N = 85) | CCRT group (N = 85) | P value |
|---|---|---|---|
Hematological | |||
Leukopenia | 33 (38.8%) | 18 (21.2%) | 0.012 |
Neutropenia | 32 (37.6%) | 10 (11.8%) | < 0.001 |
Anemia | 9 (10.6%) | 3 (3.5%) | 0.030 |
Thrombocytopenia | 8 (9.4%) | 2 (2.4%) | 0.120 |
Non-hematological | |||
Mucositis | 18 (21.2%) | 22 (25.9%) | 0.471 |
Xerostomia | 1 (1.2%) | 0 (0%) | 0.317 |
Dermatitis | 1 (1.2%) | 1 (1.2%) | 1.00 |
Nausea/ vomiting | 8 (9.4%) | 3 (3.5%) | 0.120 |
Hepaotoxicity | 5 (5.9%) | 5 (5.9%) | 1.000 |