Skip to main content

Table 1 Dose constraints of normal tissue

From: Fatigue following radiotherapy of low-risk early breast cancer – a randomized controlled trial of intraoperative electron radiotherapy versus standard hypofractionated whole-breast radiotherapy: the COSMOPOLITAN trial (NCT03838419)

Organ at risk

Dose constraints

Heart

Dmean < 3 Gy, Dmax < 30 Gy (minor violation < 40 Gy)

Ipsilateral Lung

Dmean < 8 Gy, V20Gy < 10% (minor violation < 15%)

Contralateral Breast

Dmean < 3 Gy, Dmax < 20 Gy

Spinal cord

Dmax < 45 Gy