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Table 2 Patient and tumor baseline characteristics and locations of nodal relapses

From: PET/CT of breast cancer regional nodal recurrences: an evaluation of contouring atlases

  All patients
N = 69
RNI
N = 30
Tangent only
N = 16
No RT
N = 23
P-value
Age
Median (Range)
 49 (29–84)48.5 (30–76)52 (35–75)48 (29–84)0.45
LateralityRight34 (49%)14 (47%)8 (50%)12 (52%)0.92
Left35 (51%)16 (53%)8 (50%)11 (48%)
Grade16 (9%)1 (3%)1 (6%)4 (17%)0.27
227 (39%)11 (37%)8 (50%)8 (35%)
332 (46%)17 (57%)6 (38%)9 (40%)
Unknown4 (4%)1 (3%)1 ((6%)2 (9%)
Tumor size0-2 cm32 (46%)10 (33%)11 (69%)11 (48%)0.03
> 2–5 cm26 (38%)12 (40%)5 (31%)9 (40%)
>  5 cm9 (14%)8 (27%)0 (0%)1 (4%)
Unknown2 (3%)0 (0%)0 (0%)2 (9%)
Number of positive nodes032 (46%)5 (17%)14 (88%)13 (57%)< 0.01
1–319 (28%)13 (43%)2 (12%)4 (17%)
≥ 414 (20%)11 (37%)0 (0%)3 (13%)
Unknown4 (6%)1 (3%)0 (0%)3 (13%)
StageI24 (35%)6 (20%)6 (38%)12 (52%)< 0.01
II28(40%)16 (54%)6 (38%)6 (26%)
III6(9%)4 (13%)0 (0%)2 (9%)
Unknown11(16%)4 (13%)4 (24%)3 (13%)
Her2 statusPositive6 (9%)4 (13%)1 (6%)1 (4%)0.54
Negative40 (58%)19(63%)9 (56%)12 (52%)
Unknown23 (33%)7 (23%)6 (38%)10 (44%)
Estrogen statusPositive47 (68%)17 (57%)12 (75%)18 (78%)0.11
Negative20 (29%)13 (43%)3 (19%)4 (17%)
Unknown2 (3%)0 (0%)1 (6%)1 (4%)
SurgeryBCS31 (45%)10 (33%)13 (81%)8 (35%)< 0.01
Mastectomy38 (55%)20 (66%)3 (19%)15 (65%)
Axillary lymph node dissectionYes53 (77%)27 (90%)12 (75%)14 (61%)0.04
No16 (23%)3 (10%)4 (25%)9 (31%)
ChemotherapyYes46 (67%)23 (77%)12 (75%)11 (48%)0.07
No23 (33%)7 (23%)4 (25%)12 (52%)
Hormone therapyYes41 (59%)16 (53%)12 (75%)13 (57%)0.14
No28(41%)14 (47%)4 (25%)10 (43%)
Isolated RNR
RNR and distant metastases
 31 (45%)9 (30%)9 (56%)13 (57%)0.09
 38 (55%)21 (70%)7 (44%)10 (43%)
Number of RNR 226924886 
RNR per Patient 3.33.13.03.70.28
RNR LocationsSCF
(CTV4)
352078 
(ESTRO CTV)Axilla Level 1 (CTV1)64221527 
 Axilla Level 2 (CTV2)277812 
 Interpectoral11515 
 Axilla Level 3 (CTV3)3412616 
 IMN341879 
 RADCOMP
Posterior Neck
21849 
  1. Abbreviation: RNR Regional nodal recurrence