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Table 1 Studies of regional nodal relapses in relation to nodal contouring atlases

From: PET/CT of breast cancer regional nodal recurrences: an evaluation of contouring atlases

 Total no. patients (nodes)Inclusion criteriaNo. relapsed patients (nodes)Nodal area assessedNo. patients received adjuvant RNIImaging technique for relapseNodal mapping techniqueNodal contours or epicentresNodal Atlases
Studied
Brown et al. 2015 [13]62 (161)De novo and relapse18 (44)SCF4CT/PET
or MRI
Manual mapping Template patientEpicentreRTOG
Gentile et al. 2015 [14]30 (309)De novo only0 (0)AxillaNACT scanRigid fusion
Individual
ContoursRTOG
Jing et al. 2015 [15]55 (524)De novo and relapse38 (NA)SCF3CT scan or FDG/PETManual mapping
Template patient
Epicentres + contoursRTOG
Jethwa et al. 2016 [16]130 (67)De novo and relapse7 (15)IMNNACT, PET/CT or MRIManual mapping
Template patient
EpicentresRTOG
Chang et al. 2017 [17]129 (235)Relapse only129 (235)All49CT scanManual mapping Template patientEpicentresRTOG
ESTRO
Chang et al. 2018 [18]234 (337)Relapse only234 (337)All130CT scan or
PET/CT
Manual mapping
Template patient
EpicentresRTOG
ESTRO
Borm et al. 2018 [19]235 (580)De novo and relapse197 (410)AllNAPET/CTDeformable registration
Template patient
ContoursRTOG
ESTRO
DeSelm et al. 2018 [20]153 (243)Relapse only153 (243)AllNACT, PET/CT or MRIManual mapping
Template patient
EpicentresRTOG
ESTRO
Kowlaski et al. 2019 [22]102 (389)Not statedNot statedAllNAPET/CTManual mapping Template patientEpicentresRTOG
ESTRO
RADCOMP
Almahariq et al. 2020 [21]106 (107)De novo only0 (0)Axilla Level INACT or PET, Biopsy ClipManual mapping Template patientEpicentresRTOG
ESTRO
RADCOMP
Current study69 (226)Relapse only69 (226)All30PET/CTDeformable registration
Template patient
EpicentersRTOG
ESTRO
RADCOMP