Table 1 Studies of regional nodal relapses in relation to nodal contouring atlases
From: PET/CT of breast cancer regional nodal recurrences: an evaluation of contouring atlases
Total no. patients (nodes) | Inclusion criteria | No. relapsed patients (nodes) | Nodal area assessed | No. patients received adjuvant RNI | Imaging technique for relapse | Nodal mapping technique | Nodal contours or epicentres | Nodal Atlases Studied | |
|---|---|---|---|---|---|---|---|---|---|
Brown et al. 2015 [13] | 62 (161) | De novo and relapse | 18 (44) | SCF | 4 | CT/PET or MRI | Manual mapping Template patient | Epicentre | RTOG |
Gentile et al. 2015 [14] | 30 (309) | De novo only | 0 (0) | Axilla | NA | CT scan | Rigid fusion Individual | Contours | RTOG |
Jing et al. 2015 [15] | 55 (524) | De novo and relapse | 38 (NA) | SCF | 3 | CT scan or FDG/PET | Manual mapping Template patient | Epicentres + contours | RTOG |
Jethwa et al. 2016 [16] | 130 (67) | De novo and relapse | 7 (15) | IMN | NA | CT, PET/CT or MRI | Manual mapping Template patient | Epicentres | RTOG |
Chang et al. 2017 [17] | 129 (235) | Relapse only | 129 (235) | All | 49 | CT scan | Manual mapping Template patient | Epicentres | RTOG ESTRO |
Chang et al. 2018 [18] | 234 (337) | Relapse only | 234 (337) | All | 130 | CT scan or PET/CT | Manual mapping Template patient | Epicentres | RTOG ESTRO |
Borm et al. 2018 [19] | 235 (580) | De novo and relapse | 197 (410) | All | NA | PET/CT | Deformable registration Template patient | Contours | RTOG ESTRO |
DeSelm et al. 2018 [20] | 153 (243) | Relapse only | 153 (243) | All | NA | CT, PET/CT or MRI | Manual mapping Template patient | Epicentres | RTOG ESTRO |
Kowlaski et al. 2019 [22] | 102 (389) | Not stated | Not stated | All | NA | PET/CT | Manual mapping Template patient | Epicentres | RTOG ESTRO RADCOMP |
Almahariq et al. 2020 [21] | 106 (107) | De novo only | 0 (0) | Axilla Level I | NA | CT or PET, Biopsy Clip | Manual mapping Template patient | Epicentres | RTOG ESTRO RADCOMP |
Current study | 69 (226) | Relapse only | 69 (226) | All | 30 | PET/CT | Deformable registration Template patient | Epicenters | RTOG ESTRO RADCOMP |