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Table 3 Predictive significance of clinical factors for late grade 2 toxicities

From: Preliminary result of carbon-ion radiotherapy using the spot scanning method for prostate cancer

 

Univariate

  

Multivariate

  
 

OR

(95% CI)

p-value

OR

(95% CI)

p-value

Late grade 2 GU toxicity (n = 17)

 Age

1.00

(0.93–1.07)

0.986

1.01

(0.93–1.09)

0.863

 Risk group

0.68

(0.30–1.56)

0.363

1.31

(0.27–6.45)

0.741

 ADT duration

0.98

(0.93–1.02)

0.337

0.96

(0.88–1.05)

0.407

 DM

3.32

(0.99–11.15)

0.052

2.94

(0.80–10.82)

0.105

 Anticoagulants

0.31

(0.04–2.38)

0.258

0.26

(0.03–2.28)

0.227

 BPH

1.72

(0.36–8.14)

0.496

NA

–

–

 TURP

15.60

(2.05–118.58)

0.008

NA

–

–

Late grade 2 GI toxicity (n = 3)

 Age

1.07

(0.90–1.29)

0.438

1.09

(0.0.88–1.35)

0.422

 Risk group

NA

–

–

NA

–

–

 ADT duration

1.02

(0.97–1.08)

0.403

0.98

(0.82–1.18)

0.850

 DM

4.93

(0.43–56.53)

0.199

6.27

(0.42–94.06)

0.184

 Anticoagulants

2.63

(0.23–29.64)

0.435

1.15

(0.08–16.27)

0.920

 BPH

NA

–

–

NA

–

–

 TURP

NA

–

–

NA

–

–

  1. OR Odds ratios, CI Confidence interval, NA not available, GU genitourinary, GU gastrointesitinal, ADT androgen deprivation therapy, DM diabetes mellitus, BPH benign prostate hyperplasia, TURP transurethral resection of the prostate