Table 3 Univariate and multivariate analysis of clinical parameters regarding OS in nonagenarian patients receiving radiotherapy. Pre-therapeutic parameters which were significant in the univariate analysis were included in the multivariate analysis
From: Radiotherapy for nonagenarians: the value of biological versus chronological age
| Â | HR | CI 95% | p-value |
|---|---|---|---|
Univariate analysis | |||
 Age 95–99 years / 90–94 years | 1.44 | 0.84–2.47 | 0.19 |
 ECOG 2–3 / 0–1 | 1.56 | 1.00–2.45 | 0.05 |
 ACE-27 1–3 / 0 | 2.02 | 1.00–4.10 | 0.05 |
 Split-course / no split-course | 2.05 | 1.07–3.94 | 0.03 |
 Radiotherapy not completed / completed | 7.17 | 3.88–13.26 | 0.00 |
 Palliative treatment / curative treatment | 2.84 | 1.68–4.81 | 0.00 |
 No Chemotherapy / chemotherapy | 1.02 | 0.32–3.26 | 0.98 |
 No endocrine treatment / endocrine treatment | 1.26 | 0.75–2.11 | 0.38 |
 Non-skin cancer / skin cancer | 0.87 | 0.56–1.36 | 0.54 |
 UICC stage I – II / III – IV | 2.21 | 1.14–4.26 | 0.02 |
 Inpatient / outpatient | 1.64 | 1.05–2.55 | 0.03 |
Multivariate analysis | |||
 ECOG 2–3 / 0–1 | 1.49 | 0.91–2.43 | 0.11 |
 ACE-27 1–3 / 0 | 2.37 | 0.91–6.18 | 0.08 |
 Split-course / no split-course | 2.21 | 1.10–4.37 | 0.02 |
 Palliative treatment / curative treatment | 3.19 | 1.77–5.75 | 0.00 |
 UICC stage I – II / III – IV | 1.68 | 0.76–3.74 | 0.20 |
 Inpatient / outpatient | 1.18 | 0.71–1.94 | 0.53 |