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Table 3 Univariate and multivariate analysis of clinical parameters regarding OS in nonagenarian patients receiving radiotherapy. Pre-therapeutic parameters which were significant in the univariate analysis were included in the multivariate analysis

From: Radiotherapy for nonagenarians: the value of biological versus chronological age

  HR CI 95% p-value
Univariate analysis
 Age 95–99 years / 90–94 years 1.44 0.84–2.47 0.19
 ECOG 2–3 / 0–1 1.56 1.00–2.45 0.05
 ACE-27 1–3 / 0 2.02 1.00–4.10 0.05
 Split-course / no split-course 2.05 1.07–3.94 0.03
 Radiotherapy not completed / completed 7.17 3.88–13.26 0.00
 Palliative treatment / curative treatment 2.84 1.68–4.81 0.00
 No Chemotherapy / chemotherapy 1.02 0.32–3.26 0.98
 No endocrine treatment / endocrine treatment 1.26 0.75–2.11 0.38
 Non-skin cancer / skin cancer 0.87 0.56–1.36 0.54
 UICC stage I – II / III – IV 2.21 1.14–4.26 0.02
 Inpatient / outpatient 1.64 1.05–2.55 0.03
Multivariate analysis
 ECOG 2–3 / 0–1 1.49 0.91–2.43 0.11
 ACE-27 1–3 / 0 2.37 0.91–6.18 0.08
 Split-course / no split-course 2.21 1.10–4.37 0.02
 Palliative treatment / curative treatment 3.19 1.77–5.75 0.00
 UICC stage I – II / III – IV 1.68 0.76–3.74 0.20
 Inpatient / outpatient 1.18 0.71–1.94 0.53