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Table 1 Clinicopathological characteristics of the patients before and after propensity score matching

From: Postoperative adjuvant chemotherapy versus chemoradiotherapy for node-positive esophageal squamous cell carcinoma: a propensity score-matched analysis

  

Before PSM

   

After PSM

  
 

All n = 859

S + CT

n = 609 (%)

S + CRT

n = 250 (%)

P-value

All n = 494

S + CT n = 247(%)

S + CRT

n = 247 (%)

P-value

Age, years

   

0.301

   

1.000

≤65

674(78.46)

484(79.5)

190(76)

 

377(76.32)

189(76.5)

188(76.1)

 

> 65

185(21.54)

125(20.5)

60(24)

 

117(23.68)

58(23.5)

59(23.9)

 

Sex

   

0.580

   

0.215

Male

735(85.56)

518(85.1)

217(86.8)

 

417(84.41)

203(82.2)

214(86.6)

 

Female

124(14.44)

91(14.9)

33(13.2)

 

77(15.59)

44(17.8)

33(13.4)

 

KPS score

   

0.001

   

0.786

90-100

399(46.45)

260(42.7)

139(55.6)

 

278(56.28)

141(57.1)

137(55.5)

 

70-80

460(53.55)

349(57.3)

111(44.4)

 

216(43.72)

106(42.9)

110(44.5)

 

Surgery type

   

0.010

   

0.279

Open

540(62.86)

400(65.7)

140(56)

 

265(53.64)

126(51)

139(56.3)

 

MIE

319(37.14)

209(34.3)

110(44)

 

229(46.36)

121(49)

108(43.7)

 

lymph node dissection

  

< 0.001

   

0.917

two fields

516(60.07)

326(53.5)

190(76)

 

372(75.3)

185(74.9)

187(75.7)

 

three fields

343(39.93)

283(46.5)

60(24)

 

122(24.7)

62(25.1)

60(24.3)

 

Pathological differentiation

  

0.305

   

0.671

Well (G1)

111(12.92)

76(12.5)

35(14)

 

73(14.78)

39(15.8)

34(13.8)

 

Moderate (G2)

366(42.61)

252(41.4)

114(45.6)

 

215(43.52)

103(41.7)

112(45.3)

 

Poor or undifferentiated (G3–4)

382(44.47)

281(46.1)

101(40.4)

 

206(41.7)

105(42.5)

101(40.9)

 

Location

   

< 0.001

   

0.449

Upper site

166(19.32)

92(15.1)

74(29.6)

 

134(27.13)

62(25.1)

72(29.1)

 

Middle site

456(53.08)

323(53)

133(53.2)

 

265(53.64)

133(53.8)

132(53.4)

 

Lower site

237(27.59)

194(31.9)

43(17.2)

 

95(19.23)

52(21.1)

43(17.4)

 

Resection

   

0.002

   

0.430

R0

803(93.48)

580(95.2)

223(89.2)

 

450(91.09)

228(92.3)

222(89.9)

 

R1-2

56(6.52)

29(4.8)

27(10.8)

 

44(8.91)

19(7.7)

25(10.1)

 

Varscular Invasion

  

0.210

   

0.397

Yes

647(75.32)

451(74.1)

196(78.4)

 

377(76.32)

184(74.5)

193(78.1)

 

No

212(24.68)

158(25.9)

54(21.6)

 

117(23.68)

63(25.5)

54(21.9)

 

Nerve invasion

   

1.000

   

0.391

Yes

677(78.81)

480(78.8)

197(78.8)

 

381(77.13)

186(75.3)

195(78.9)

 

No

182(21.19)

129(21.2)

53(21.2)

 

113(22.87)

61(24.7)

52(21.1)

 

Dissection nodes

   

0.394

   

0.652

≤20

406(47.26)

294(48.3)

112(44.8)

 

226(45.75)

116(47)

110(44.5)

 

> 20

453(52.74)

315(51.7)

138(55.2)

 

268(54.25)

131(53)

137(55.5)

 

Pathological T status

  

< 0.001

   

0.130

T1

42(4.89)

30(4.9)

12(4.8)

 

18(3.64)

6(2.4)

12(4.9)

 

T2

148(17.23)

110(18.1)

38(15.2)

 

74(14.98)

36(14.6)

38(15.4)

 

T3

573(66.71)

419(68.8)

154(61.6)

 

329(66.6)

175(70.9)

154(62.3)

 

T4a

87(10.13)

49(8)

38(15.2)

 

67(13.56)

29(11.7)

38(15.4)

 

T4b

9(1.05)

1(0.2)

8(3.2)

 

6(1.21)

1(0.4)

5(2)

 

Pathological N status

  

0.057

   

0.327

N1

455(52.97)

320(52.5)

135(54)

 

281(56.88)

148(59.9)

133(53.8)

 

N2

270(31.43)

183(30)

87(34.8)

 

157(31.78)

71(28.7)

86(34.8)

 

N3

134(15.6)

106(17.4)

28(11.2)

 

56(11.34)

28(11.3)

28(11.3)

 

Pathological TNM stage

  

0.896

   

0.629

IIB

28(3.26)

20(3.3)

8(3.2)

 

13(2.63)

5(2)

8(3.2)

 

IIIA

97(11.29)

72(11.8)

25(10)

 

52(10.53)

27(10.9)

25(10.1)

 

IIIB

562(65.42)

396(65)

166(66.4)

 

341(69.03)

175(70.9)

166(67.2)

 

IVA

172(20.02)

121(19.9)

51(20.4)

 

88(17.81)

40(16.2)

48(19.4)

 
  1. Note: AJCC American Joint Committee on Cancer, S Surgery alone, S + CT Postoperative chemotherapy, S + CRT postoperative chemoradiotherapy, OS Overall survival, DFS Disease-free survival, HR Hazard ratio, CI Confident interval, KPS Karnofsky Performance Status, MIE Minimally invasive esophagectomy