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Table 2 Dosimetric analysis of organs at risk

From: Feasibility of hippocampus-sparing VMAT for newly diagnosed glioblastoma treated by chemoradiation: pattern of failure analysis

Organs at risk

Dose (Gy)

Median

interquartile range

Hippocampus

Contralateral

Vol (cc)

1.70

1.40

2.15

D100%

6.71

2.96

9.70

Dmax

16.10

13.30

16.85

Dmean

10.94

7.59

12.58

Dmean (EQD2/2)

6.59

4.27

7.61

Ipsilaterala

Vol (cc)

1.50

1.05

1.80

D100%

8.44

2.66

16.69

Dmax

46.69

16.70

57.52

Dmean

19.70

8.54

38.86

Dmean (EQD2/2)

13.22

4.89

32.62

Bilaterala

Dmean

15.15

8.31

25.01

Dmean (EQD2/2)

9.59

4.75

18.44

Optic chiasm

Dmax

36.60

18.85

50.70

Optic nerve

Dmax

14.90

2.37

46.99

Brain stem

Dmax

51.77

22.40

59.54

Eyeballs

Dmax

6.18

1.99

21.81

Lenses

Dmax

2.08

0.93

5.19

  1. Abbreviations: EQD2/2 equivalent dose in 2-Gy fraction assuming alpha-beta ratio of 2 Gy
  2. aExcluded for analysis if whole ipsilateral hippocampus was included within the planning target volume