Risk factors for esophagitis after hypofractionated palliative (chemo) radiotherapy for non-small cell lung cancer

Table 2 Risk factors for esophagitis (yes/no; grade 1–3 combined), univariate analysis

Parameter	Odds ratio (95% confidence interval)	p-value
Concomitant chemotherapy (yes/no)	5.99 (2.30–15.50)	0.0001*
Concomitant steroid use (no/yes)	3.00 (1.13–7.94)	0.023*
Dmax esophagus	1.13 (1.04–1.23)	0.004**
Dmean esophagus	1.10 (1.03–1.18)	0.002**
V20 esophagus	1.04 (1.01–1.07)	0.001**
V30 esophagus	1.04 (1.01–1.06)	0.001**
V35 esophagus	1.04 (1.01–1.06)	0.001**
V40 esophagus	1.04 (1.01–1.07)	0.002**
Dose to 5 cc of esophagus	1.07 (1.02–1.12)	0.005**

Not significant: age, sex, T stage, N stage, smoking, history of gastroesophageal reflux disease, dose to 10 cc esophagus, esophagus volume inside PTV
* Chi-square test
** Binary logistic regression analysis

ISSN: 1748-717X