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Table 1 Patients’ and disease characteristics (n = 142)

From: Prognostic impact of the “Sekhar grading system for cranial Chordomas” in patients treated with pencil beam scanning proton therapy: an institutional analysis

Age at diagnosismedian (range)
42 (1–79)
Gendern (%)
 Female66 (46)
 Male76 (53)
Histologyn (%)
 Non-chondroid136 (96)
 Chondroid6 (4)
Number of surgeries (biopsies included)n (%)
 175 (53)
 246 (32)
  > 221 (15)
Maximal extent of resectionn (%)
 Gross total resection19 (13)
 Subtotal resection118 (83)
 Biopsy5 (4)
Surgical complicationsn (%)
 No88 (62)
 Yes54 (38)
Brainstem compression before PTn (%)
 No105 (74)
 Abuttment27 (19)
 Yes10 (7)
Optic pathway compression before PTn (%)
 No121 (85)
 Abuttment15 (11)
 Yes6 (4)
Any compression/abuttment before PTn (%)
 No88 (62)
 Yes54 (38)
Delivered dose in GyRBEmedian (range)
 Total dose74.0 (72.6–80.0)
 Single dose2.0 (1.8–2.5)
GTV in ccmedian (range)
26.3 (0.0–130.4)
PT for recurrent diseasen (%)
 No120 (85)
 Yes22 (15)
  1. PT proton therapy, GyRBE relative biological effective dose in gray, GTV gross tumor volume, cc cm3