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Table 2 Univariable and multivariable competing risk regression accounting for clustered analysis and competing risk of death

From: Predicting per-lesion local recurrence in locally advanced non-small cell lung cancer following definitive radiation therapy using pre- and mid-treatment metabolic tumor volume

 Local recurrence (n = 45 events)  
Variable UnivariableMVA1MVA2
AgeHR1.00  
95% CI0.96–1.05  
P0.84  
ΔMTVHR1.09  
95% CI0.96–1.24  
P0.19  
Log(MTVpre)HR2.43 2.01
95% CI1.56–3.78 1.25–3.23
P8.4e-5 0.004
Log(MTVmid)HR2.332.12 
95% CI1.61–3.371.47–3.08 
P6.8e-57.1e-5 
Primary Lesion (non-nodal target)HR3.601.371.79
95% CI1.86–6.950.67–2.790.86–3.72
P0.00010.380.12
RT doseHR1.06  
95% CI0.97–1.16  
P0.17  
Histology
 Adenocarcinoma (ref)HR  
95% CI  
P  
 SCCHR1.89  
95% CI0.80–4.46  
P0.15  
 All othersHR1.27  
95% CI0.30–5.45  
P0.75  
  1. Abbreviations: MVA multivariable analysis; MTVpre pretreatment metabolic tumor volume; MTVmid mid-treatment metabolic tumor volume; RT radiation therapy; SCC squamous cell carcinoma; ref. reference