Factors affecting outcome in frameless non-isocentric stereotactic radiosurgery for trigeminal neuralgia: a multicentric cohort study

Table 6 Univariate and multivariate Cox regression analyses for factors affecting the occurrence of numbness

	Univariate Analyses			Multivariate Analysis
	HR	95% CI	p-value	HR	95% CI	p-value
Age	0.994	0.978–1.012	0.519
Gender	0.906	0.566–1.450	0.681
Volume	0.987	0.970–1.005	0.148
Integral dose	0.787	0.594–1.044	0.097	0.789	0.603–1.033	0.085
D_mean	0.973	0.937–1.010	0.155	1.024	0.986–1.064	0.214
Isodose	1.106	1.016–1.204	0.021	1.072	0.978–1.176	0.136
D_max	0.969	0.938–1.002	0.062
Prescription dose	0.977	0.836–1.019	0.281
Re-irradiation yes/no no as reference	4.446	2.667–7.412	0.000	5.814	3.252–10.295	0.000
Multiple sclerosis yes/no no as reference	0.390	0.167–0.908	0.024	0.196	0.079–0.484	0.000

ISSN: 1748-717X