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Table 3 10-year cardiovascular cumulative risk of 210 left-sided breast cancer patients following radiotherapy after taking into account an increase of 7.4% per Gy in mean heart dose of the individual treatment plans. FB: free-breathing, DIBH: deep inspiration breath-hold, EAR: excess absolute risk

From: Heart sparing radiotherapy in breast cancer: the importance of baseline cardiac risks

 

Non-Diabetic patients (n = 200)

Diabetic patients (n = 10)

Entire cohort (n = 210)

Following FB-RT

Following DIBH-RT

Following FB-RT

Following

DIBH-RT

Following FB-RT

Following DIBH-RT

Procam Score

Baseline risk

3.11%

11.76%

3.52%

Mean EAR

+ 0.50%

+ 0.30%

+ 1.92%

+ 1.52%

+ 0.57%

+ 0.36%

Mean cumulative risk

3.61%

3.41%

13.68%

13.28%

4.09%

3.88%

Framingham Score

Baseline risk

3.39%

24.23%

4.38%

Mean EAR

+ 0.55%

+ 0.34%

+ 4.64%

+ 3.37%

+ 0.75%

+ 0.49%

Mean cumulative risk

3.94%

3.73%

28.87%

27.60%

5.13%

4.87%

Reynolds Score

Baseline risk

3.58%

10.66%

3.91%

Mean EAR

+ 0.60%

+ 0.37%

+ 1.88%

+ 1.47%

+ 0.67%

+ 0.42%

Mean cumulative risk

4.18%

3.95%

12.54%

12.13%

4.58%

4.33%