Fig. 1

Box plot of mean 10-year baseline cardiovascular disease (CVD) risk of 200 non-diabetic patients (a) and 10 diabetic patients (b) as calculated by different risk estimation tools (white bars); and absolute mean 10-year cumulative CVD risk after left-sided breast radiotherapy in DIBH after taking into account a linear increase of 7.4% per Gy mean heart dose (grey bars). In the box plots, the boundary of the box closest to zero indicates the 25th percentile, a black line within the box marks the median and the boundary of the box farthest from zero indicates the 75 th percentile. Whiskers above and below the box indicate the 1.5 interquartile range (IQR). Points above and below the whiskers indicate outliers outside the 1.5 IQR (1.5–3 IQR) and > 3 IQR