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Table 3 Univariate and multivariate analyses on local control (LC)

From: Brain metastases treated with hypofractionated stereotactic radiotherapy: 8 years experience after Cyberknife installation

Univariate analyses

Multivariate analyses

Variable

N

HR

IC95%

p

HR

IC95%

p

Size

N = 378

  

0.0178

   

0,0072

 > =2.5 cm vs < 2.5 cm

 

1.699

[1.096–2.634]

 

1.909

[1.191–3.060]

 

Fractionation

N = 400

  

0.3902

   

0,2072

 30 Gy in 5 vs 27 Gy in 3

 

1.331

[0.823–2.151]

 

0.917

[0.508–1.655]

 

 35 Gy in 5 vs 27 Gy in 3

 

0.955

[0.553–1.649]

 

1.453

[0.853–2.477]

 

Control of primary tumor

N = 383

  

0.0598

    

 Yes vs No

 

0.661

[0.429–1.017]

     

Systemic treatment

N = 382

  

0.9556

    

 Yes vs No

 

0.987

[0.630–1.546]

     

Surgery

N = 400

  

0.0490

   

0,0044

 Yes vs no

 

1.816

[1.002–3.289]

 

2.506

[1.333–4.712]

 

Group

N = 400

  

0.0490

    

 Surgery + HFSRT vs HFSRT

 

0.551

[0.304–0.998]

 

0.437

[0.235–0.812]

0,0088

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Radiation Oncology

ISSN: 1748-717X

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