Whole brain radiation therapy plus focal boost may be a suitable strategy for brain metastases in SCLC patients: a multi-center study

Table 1 Baseline characteristics of patients before propensity score matching

	WBRT + boost	WBRT Alone	SRS Alone	P Value
	(n = 79)	(n = 140)	(n = 44)	P Value
Age, No. (%)				0.563
< 60	36	67	17
≥60	43	73	27
Sex, No. (%)				0.819
Male	55	103	32
Female	24	37	12
KPS, No. (%)				0.931
≤80	47	84	25
> 80	32	56	19
Number of BMs, No. (%)				< 0.001
1–3	51	34	39
> 3	28	106	5
Maximum size of BM, No. (%)				0.170
< 20 mm	36	81	26
≧20 mm	43	59	18
Extracranial metastases, No. (%)				0.009
Yes	17	53	6
None	14	20	6
Unknown	48	67	32
Symptoms of BM, No. (%)				0.123
Yes	37	69	14
None	42	71	30
Systematic treatment				0.833
CTx	55	99	29
No-CTx	24	41	15

Abbreviations: WBRT+boost whole brain radiotherapy plus focal radiation boost, WBRT whole brain radiation therapy, SRS stereotactic radiosurgery, KPS Karnofsky Performance Status, BM brain metastasis, CTx chemotherapy, No-CTx no chemotherapy

ISSN: 1748-717X