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Table 2 PTV coverage in studies comparing 3D-CRT vs. IMRT

From: Fondazione Italiana Linfomi (FIL) expert consensus on the use of intensity-modulated and image-guided radiotherapy for Hodgkin’s lymphoma involving the mediastinum

 AP-PA3D-CRTIMRT
Goodman et al [19]: IMRT 3–6 beamsV95 93%;D95 90%; Dmax 117%; Dmin 78%; MD 103%V95 95%; D95 98%; Dmax 118%; Dmin 80%; MD 106%V95 98%; D95 101%; Dmax 120%; Dmin 76%
MD 107%
Nieder et al [21]: IMRT: 7-field coplanarV95 97%V95 95%V95 96%
Chera et al [22]: 5 equally spaced beams IMRT MD 31.9 Gy; V30 96.5%; Dmax 34.2 Gy; Dmin 28.1MD 31.7 Gy; V30 97.5%; Dmax 32.7 Gy; Dmin 29.1
Cella et al [23]: Forward planned IMRTV95 95.9%, Dmax 118%, Dmin 77%, DM 105%, IC 0.40 V95 96.8%, Dmax 111%, Dmin 79%, DM 101%, CI 0.31
Koeck et al [26]: IF vs IN. Coplanar IMRT DM 29.7–29.8 Gy; V95% 85.3–90.5; V107% 0.4–0.5; CI 2.77–2.8, HI 0.82–0.85DM 28.8–29.8 Gy; V95% 86.4–87.7, V107% 2.7–2.9; CI 1.24–1.25; HI 0.77–0.78
De Sanctis et al [28]: 5 equally spaced beams IMRT MD 101.4%; Dmax 108.8%; Dmin 41.4%MD 100%: Dmax 106.6 Gy; Dmin 71.4 Gy
Fiandra et al [29]. IMRT: VMAT vs Tomodirect vs Helical Tomotherapy MD 30.6 Gy; V95 94.8%; V107 5%; HI 0.3MD 29.9–30.4 Gy; V95 95.4–97.4%; V107 0–5.5%;
HI 0.07–0.2
Chen et al [30]: IMRT Coplanar vs Non-coplanarD98% 34.4 Gy, MD 39.1 Gy; CI 0.47; HI 1.19 D98% 34.2–34.1 Gy, MD 38.4–38.3 Gy; CI 0.72–0.71; HI 1.13
Antoni et al [32]: Helical Tomotherapy CI 2.4; HI 1.1; V95 93.7%CI 1.2; HI 1.1; V95 95.8%
Voong et al [33]: butterfly IMRT, multiple arcs CI 1.66, HI 1.14, PTV dose 32.02 Gy, V107 801.5 cm3CI 1.10, HI 1.15, PTV dose 31.39 Gy
Kriz et al [35]: 5 beams vs 7 equally spaced beams.D98 92–93.5%; HI 0.14–0.47; CI 2.61–2.84 D98 92.6–93.9%; HI 0.11–0.16; CI 0.99–1.24
Besson et al [36]: TomotherapyMD 30.1 Gy, CI 2.9, HI 2.9; V90 98.1%, V95 94.7%, V100 63%, V107 1.2%. MD 30.3 Gy, CI 1.4, HI 0.5;V90 99.9%, V95 98.7%, V100 52.2%, V107 0%
Higby et al [38]: VMATV20 35.4%, V5 52.6%, MD 13 Gy V20 20.8%, V5 67.8%, MD 11.9 Gy
  1. Abbreviations: V volume, D dose, MD mean dose, HI homogeneity index, CI conformity index