Table 3 Multivariate Analysis of Dose-volume Variables Associated with Pericardial Effusion
Parameters | Pericardial effusion of any grade | Pericardial effusion ≥ Grade 3 | ||
|---|---|---|---|---|
P value | HR (95% CI) | P value | HR (95% CI) | |
Heart | ||||
Mean (Gy) | < 0.001 | 9.792 (2.930–32.724) | NA | NA |
V5 (%) | 0.001 | 6.670 (2.172–20.481) | NA | NA |
V10 (%) | 0.001 | 7.292 (2.370–22.439) | NA | NA |
V20 (%) | < 0.001 | 10.681 (2.844–40.111) | NA | NA |
V30 (%) | < 0.001 | 10.813 (2.897–40.360) | NA | NA |
V40 (%) | < 0.001 | 7.191 (2.487–20.796) | NA | NA |
V50 (%) | 0.002 | 4.977 (1.790–13.842) | NA | NA |
V60 (%) | 0.363 | 1.407 (0.674–2.937) | 0.055 | 5.495 (0.967–31.234) |
Pericardium | ||||
Mean (Gy) | < 0.001 | 9.597 (2.850–32.310) | NA | NA |
V5 (%) | 0.001 | 6.408 (2.194–18.713) | NA | NA |
V10 (%) | 0.001 | 8.507 (2.271–31.863) | NA | NA |
V20 (%) | < 0.001 | 10.324 (2.780–38.343) | NA | NA |
V30 (%) | 0.001 | 8.269 (2.503–27.319) | 0.010 | 32.309 (2.311–451.777) |
V40 (%) | < 0.001 | 7.064 (2.430–20.540) | 0.005 | 16.715 (2.307–121.093) |
V50 (%) | 0.001 | 5.312 (1.977–14.274) | NA | NA |
V60 (%) | 0.349 | 1.406 (0.689–2.868) | 0.025 | 7.545 (1.293–44.011) |