Table 2 Univariate Analysis of Dose-volume Variables Associated with Pericardial Effusion
Parameters | Pericardial effusion of any grade | Pericardial effusion ≥ Grade 3 | ||||
|---|---|---|---|---|---|---|
Cutoff | P value | HR (95% CI) | Cutoff | P value | HR (95% CI) | |
Heart | ||||||
Maximal (Gy) | 67.24 | 0.239 | 1.485 (0.769–2.870) | 55.24 | 0.222 | 3.695 (0.453–30.128) |
Mean (Gy) | 23.45 | 0.001 | 5.876 (2.068–16.697) | 30.99 | 0.133 | 81.645 (0.260–25,636.991) |
V5 (%) | 76.55 | 0.002 | 4.585 (1.776–11.835) | 92.00 | 0.126 | 93.028 (0.281–30,852.401) |
V10 (%) | 68.15 | 0.001 | 4.739 (1.837–12.224) | 84.20 | 0.134 | 81.108 (0.258–25,461.652) |
V20 (%) | 50.70 | 0.001 | 6.942 (2.118–22.753) | 73.90 | 0.137 | 77.714 (0.251–24,062.690) |
V30 (%) | 33.55 | 0.001 | 7.235 (2.204–23.749) | 57.45 | 0.130 | 85.917 (0.268–27,518.745) |
V40 (%) | 27.90 | 0.001 | 4.283 (1.864–9.841) | 31.90 | 0.137 | 77.772 (0.251–24,088.957) |
V50 (%) | 10.55 | 0.002 | 3.797 (1.653–8.723) | 10.95 | 0.161 | 60.587 (0.195–18,812.141) |
V60 (%) | 9.30 | 0.054 | 1.909 (0.988–3.690) | 26.00 | 0.021 | 7.133 (1.343–37.891) |
Pericardium | ||||||
Maximal (Gy) | 55.14 | 0.198 | 1.673 (0.764–3.663) | 53.97 | 0.406 | 27.314 (0.011–66,655.501) |
Mean (Gy) | 20.33 | 0.001 | 5.623 (1.981–15.958) | 30.18 | 0.131 | 85.491 (0.267–27,370.316) |
V5 (%) | 84.50 | 0.001 | 3.758 (1.709–8.262) | 89.15 | 0.128 | 89.096 (0.275–28,826.399) |
V10 (%) | 48.50 | 0.003 | 6.135 (1.876–20.066) | 82.65 | 0.116 | 119.578 (0.305–46,932.571) |
V20 (%) | 42.55 | 0.001 | 6.997 (2.141–22.863) | 71.55 | 0.120 | 109.854 (0.295–40,886.708) |
V30 (%) | 33.35 | 0.001 | 5.569 (1.961–15.817) | 65.80 | 0.008 | 17.537 (2.137–143.927) |
V40 (%) | 28.90 | < 0.001 | 4.120 (1.868–9.086) | 55.35 | < 0.001 | 19.316 (3.711–100.530) |
V50 (%) | 21.45 | < 0.001 | 4.262 (2.086–8.708) | 16.10 | 0.151 | 66.216 (0.215–20,359.365) |
V60 (%) | 11.10 | 0.066 | 1.838 (0.961–3.514) | 24.70 | 0.011 | 9.324 (1.676–51.885) |