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Table 5 Univariate and multivariate analyses for OS of all patients (n = 20300)

From: Neoadjuvant radiotherapy improves overall survival for T3/4N+M0 rectal cancer patients: a population-based study of 20300 patients

Variables

Level

Univariate

P value

Multivariate

P value

HR (95% CI)

HR (95% CI)

Age

≤60

1

 

1

 

> 60

2.196(2.084~2.313)

< 0.001

2.177(2.067~2.294)

< 0.001

Sex

Male

1

   

Female

0.966(0.918~1.016)

0.179

  

Race

White

1

 

1

 

Black

1.231(1.131~1.340)

< 0.001

1.226(1.126~1.335)

< 0.001

American Indian/Alaska Native

1.112(0.846~1.461)

0.447

1.213(0.923~1.595)

0.166

Asian or Pacific Islander

0.859(0.787~0.939)

0.001

0.922(0.844~1.007)

0.071

Marital status

Married

1

 

1

 

Unmarried

1.553(1.476~1.633)

< 0.001

1.456(1.384~1.533)

< 0.001

Unknown

1.186(1.027~1.369)

0.020

1.142(0.989~1.320)

0.070

Tumour grade

Low

1

 

1

 

High

1.623(1.527~1.726)

< 0.001

1.646(1.548~1.750)

< 0.001

Unknown

0.788(0.705~0.880)

< 0.001

0.807(0.722~0.902)

< 0.001

Tumour size

0~3 cm

1

 

1

 

3~5 cm

1.186(1.114~1.263)

< 0.001

1.164(1.094~1.240)

< 0.001

> 5 cm

1.443(1.353~1.539)

< 0.001

1.399(1.311~1.493)

< 0.001

  1. OS overall survival, HR Hazard ratio