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Table 5 Univariate and multivariate analyses for OS of all patients (n = 20300)

From: Neoadjuvant radiotherapy improves overall survival for T3/4N+M0 rectal cancer patients: a population-based study of 20300 patients

Variables Level Univariate P value Multivariate P value
HR (95% CI) HR (95% CI)
Age ≤60 1   1  
> 60 2.196(2.084~2.313) < 0.001 2.177(2.067~2.294) < 0.001
Sex Male 1    
Female 0.966(0.918~1.016) 0.179   
Race White 1   1  
Black 1.231(1.131~1.340) < 0.001 1.226(1.126~1.335) < 0.001
American Indian/Alaska Native 1.112(0.846~1.461) 0.447 1.213(0.923~1.595) 0.166
Asian or Pacific Islander 0.859(0.787~0.939) 0.001 0.922(0.844~1.007) 0.071
Marital status Married 1   1  
Unmarried 1.553(1.476~1.633) < 0.001 1.456(1.384~1.533) < 0.001
Unknown 1.186(1.027~1.369) 0.020 1.142(0.989~1.320) 0.070
Tumour grade Low 1   1  
High 1.623(1.527~1.726) < 0.001 1.646(1.548~1.750) < 0.001
Unknown 0.788(0.705~0.880) < 0.001 0.807(0.722~0.902) < 0.001
Tumour size 0~3 cm 1   1  
3~5 cm 1.186(1.114~1.263) < 0.001 1.164(1.094~1.240) < 0.001
> 5 cm 1.443(1.353~1.539) < 0.001 1.399(1.311~1.493) < 0.001
  1. OS overall survival, HR Hazard ratio