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Table 4 Multivariate Cox analyses of treatment modalities for OS (n = 20300)

From: Neoadjuvant radiotherapy improves overall survival for T3/4N+M0 rectal cancer patients: a population-based study of 20300 patients

 

Treatment

Multivariate

P value

HR (95% CI)

T3/4N0M0 (n = 7808)

Surgery alone

1

 

Neoadjuvant RT

0.591 (0.533~0.654)

< 0.001

Adjuvant RT

0.660 (0.581~0.749)

< 0.001

Surgery + chemo

0.598 (0.466~0.768)

< 0.001

T1/2N+M0 (n = 2163)

Surgery alone

1

 

Neoadjuvant RT

0.467 (0.372~0.587)

< 0.001

Adjuvant RT

0.378 (0.299~0.477)

< 0.001

Surgery + chemo

0.463 (0.342~0.628)

< 0.001

T3/4N+M0 (n = 10,329)

Surgery alone

1

 

Neoadjuvant RT

0.436 (0.396~0.478)

< 0.001

Adjuvant RT

0.478 (0.431~0.531)

< 0.001

Surgery + chemo

0.495 (0.431~0.568)

< 0.001

  1. Multivariate Cox analyses are adjusted by age, sex, race, marital status, tumour grade, tumour size and N stage; HR Hazard ratio, RT radiotherapy
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Radiation Oncology

ISSN: 1748-717X

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