Table 2 Patient characteristics stratified by treatment modality (n = 20300)
Characteristics | Level | Only surgery (n = 2955) | Surgery + chemotherapy (n = 1447) | Neoadjuvant RT (n = 12,133) | Adjuvant RT (n = 3765) | P value |
|---|---|---|---|---|---|---|
Age, years | Mean ± SD | 70.94 ± 13.680 | 59.60 ± 12.824 | 58.56 ± 12.305 | 60.28 ± 12.037 | – |
Median (range) | 73 (20~101) | 59 (17~92) | 58 (17~99) | 60 (21~95) | Â | |
≤60 | 708 (24.0%) | 764 (52.8%) | 6880 (56.7%) | 1931 (51.3%) | < 0.001 | |
> 60 | 2247 (76.0%) | 683 (47.2%) | 5253 (43.3%) | 1834 (48.7%) |  | |
Sex | Male | 1556 (52.7%) | 793 (54.8%) | 7547 (62.2%) | 2201 (58.5%) | < 0.001 |
Female | 1399 (47.3%) | 654 (45.2%) | 4586 (37.8%) | 1564 (41.5%) | Â | |
Race | White | 2387 (80.8%) | 1161 (80.2%) | 9827 (81.0%) | 3028 (80.4%) | 0.027 |
Black | 233 (7.9%) | 121 (8.4%) | 992 (8.2%) | 317 (8.4%) | Â | |
American Indian /Alaska Native | 9 (0.3%) | 8 (0.6%) | 117 (1.0%) | 32 (0.8%) | Â | |
Asian or Pacific Islander | 326 (11.0%) | 157 (10.9%) | 1197 (9.9%) | 388 (10.3%) | Â | |
Marital status | Married | 1408 (47.6%) | 882 (61.0%) | 7221 (59.5%) | 2323 (61.7%) | < 0.001 |
Unmarried | 1401 (47.4%) | 504 (34.8%) | 4495 (37.0%) | 1342 (35.6%) | Â | |
Unknown | 146 (4.9%) | 61 (4.2%) | 417 (3.4%) | 100 (2.7%) | Â | |
Tumour grade | Low | 2423 (82.0%) | 1163 (80.4%) | 9149 (75.4%) | 2977 (79.1%) | < 0.001 |
High | 495 (16.8%) | 250 (17.3%) | 1537 (12.7%) | 687 (18.2%) | Â | |
Unknown | 37 (1.3%) | 34 (2.3%) | 1447 (11.9%) | 101 (2.7%) | Â | |
Tumour size | 0~3 cm | 654 (22.1%) | 442 (30.5%) | 3657 (30.1%) | 1103 (29.3%) | < 0.001 |
3~5 cm | 1260 (42.6%) | 577 (39.9%) | 4752 (39.2%) | 1508 (40.1%) |  | |
> 5 cm | 1041 (35.2%) | 428 (29.6%) | 3724 (30.7%) | 1154 (30.7%) |  | |
AJCC Stage | II | 1598 (54.1%) | 343 (23.7%) | 4653 (38.3%) | 1214 (32.2%) | < 0.001 |
III | 1357 (45.9%) | 1104 (76.3%) | 7480 (61.7%) | 2551 (67.8%) | Â | |
AJCC T Stage | T1 | 93 (3.1%) | 102 (7.0%) | 168 (1.4%) | 191 (5.1%) | < 0.001 |
T2 | 240 (8.1%) | 203 (14.0%) | 699 (5.8%) | 467 (12.4%) | Â | |
T3 | 2395 (81.0%) | 1006 (69.5%) | 10,057 (82.9%) | 2765 (73.4%) | Â | |
T4 | 227 (7.7%) | 136 (9.4%) | 1209 (10.0%) | 342 (9.1%) | Â | |
AJCC N Stage | N0 | 1598 (54.1%) | 343 (23.7%) | 4653 (38.3%) | 1214 (32.2%) | < 0.001 |
N1 | 889 (30.1%) | 717 (49.6%) | 5598 (46.1%) | 1541 (40.9%) | Â | |
N2 | 468 (15.8%) | 387 (26.7%) | 1882 (15.5%) | 1010 (26.8%) | Â | |
Chemotherapy | Yes | 0 (0.0%) | 1447 (100.0%) | 11,890 (98.0%) | 3445 (91.5%) | < 0.001 |
No/Unknown | 2955 (100.0%) | 0 (0.0%) | 243 (2.0%) | 320 (8.5%) | Â |