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Table 1 Baseline demographic, tumor, and treatment characteristics of 374 NPC patients

From: Radiation-induced lymphopenia correlates with survival in nasopharyngeal carcinoma: impact of treatment modality and the baseline lymphocyte count

Characteristic

Result

Sex, N (%)

 Female

112 (29.9)

 Male

262 (70.1)

Age at diagnosis, years (median, range)

46 (17–70)

ALC baseline before treatment ×109 cells/L (median, range)

1.81 (0.25–3.5)

Body mass index, kg/m2 (median, range)

22.60 (15.60–33.77)

Smoking status, pack*year (median,range)

0 (0–120)

Tumor histologic type (WHO), N (%)

 Non-keratinized undifferentiated (III)

145 (38.8)

 Non-keratinized differentiated (II)

220 (58.8)

 Keratinized (I)

9 (2.41)

T status, N (%)

 T1

37 (9.9)

 T2

133 (35.6)

 T3

156 (41.7)

 T4

48 (12.8)

N status, N (%)

 N0

31 (82.9)

 N1

80 (21.4)

 N2

227 (60.7)

 N3

36 (9.6)

Stagea, N (%)

 II

46 (12.3)

 III

245 (65.5)

 IVa

83 (22.2)

Prescribed dose of GTVnx,Gy, (median, range)

72.7 (68–82)

Induction or concurrent chemotherapy, N (%)

 None

48 (12.8)

 Induction only

62 (16.6)

 Concurrent only

70 (18.7)

 Both

194 (51.9)

Adjuvant chemotherapy, N (%)

 Yes

131 (35.0)

 No

243 (65.0)

Radiation modality, N (%)

 2D-CRT

261 (69.8)

 IMRT

113 (30.2)

  1. Abbreviations: CI confidence interval, HR hazard ratio, 2D-CRT 2-dimensional conventional radiotherapy, IMRT intensity modulated radiation therapy, GTV gross tumor volume, WHO World Health Organization, ALC absolute lymphocyte count
  2. aAmerican Joint Committee on Cancer, eighth edition