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Table 2 Investigations’ characteristics in category C and D

From: Where is clinical research for radiotherapy going? Cross-sectional comparison of past and contemporary phase III clinical trials

 

Past years (Jan 2000 – Dec 2004)

Contemporary years (July 2014 – June 2018)

P value

Category C

  

0.364

 Sensitizer

6

4

 General tolerability or Pain

6

6

 Specific toxicity

6

12

  - Skin reaction

- 1

- 4

  - Oral mucositis

- 3

- 7

  - Xerostomia

- 2

- 0

  - Urinary symptom

- 0

- 1

Category D

  

0.002

 Cytotoxic drug

14

17

 New drug

2

12

  - Targeted agent

- 2

- 8

  - Immunotherapy

- 0

- 3

  - Antivirals

- 0

- 1

 Surgery

2

0