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Table 2 Averaged results and comparison of dosimetric parameters using dac-VMAT and sapf-VMAT. Each value was calculated based on the data from 20 patients and was expressed as mean ± standard deviation (SD)

From: Volumetric modulated arc therapy (VMAT) for hippocampal-avoidance whole brain radiation therapy: planning comparison with Dual-arc and Split-arc partial-field techniques

Structures

Dosimetric Parameters

dac-VMAT

sapf-VMAT

p-value

Whole Brain PTV

V30Gy (%)

94.67 ± 0.25

94.79 ± 0.13

p = 0.358

D2% (Gy)

33.04 ± 0.32

33.12 ± 0.34

p = 0.842

D98% (Gy)

26.11 ± 0.06

25.84 ± 0.03

p = 0.401

HI

0.22 ± 0.02

0.23 ± 0.01

p = 0.435

Hippocampus

D100% (Gy)

9.23 ± 0.13 **

7.86 ± 0.08 **

p < 0.001

Dmax (Gy)

16.33 ± 0.63 **

13.23 ± 0.46 **

p < 0.001

Dmean (Gy)

10.85 ± 0.21 **

9.16 ± 0.10 **

p < 0.001

Left Optic Nerve

Dmax (Gy)

30.80 ± 0.66

31.23 ± 0.48

p = 0.791

Right Optic Nerve

Dmax (Gy)

30.82 ± 0.55

30.51 ± 0.61

p = 0.567

Optic Chiasm

Dmax (Gy)

32.36 ± 0.26

32.48 ± 0.25

p = 0.939

Left Eye

Dmax (Gy)

16.83 ± 0.75

17.12 ± 0.47

p = 0.481

Dmean (Gy)

10.46 ± 0.56 *

9.34 ± 0.32 *

p = 0.026

Right Eye

Dmax (Gy)

17.26 ± 0.63

17.21 ± 0.26

p = 0.991

Dmean (Gy)

10.36 ± 0.46 *

9.07 ± 0.33 *

p = 0.042

Left Lens

Dmax (Gy)

7.32 ± 0.54

7.33 ± 0.25

p = 0.679

Right Lens

Dmax (Gy)

7.53 ± 0.44

7.12 ± 0.41

p = 0.985

Total MU

919.69 ± 130.95

1085.58 ± 153.57

p = 0.053

Beam-on time (minute)

3.14 ± 0.11

3.04 ± 0.22

p = 0.446

Delivery time (minute)

3.41 ± 0.11

3.62 ± 0.22

p = 0.437

  1. * p < 0.05;
  2. ** p < 0.005 (paired t-test)