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Table 1 Detailed clinical characteristics of the patients enrolled in this study (N = 169)

From: Impact of genetic variant of HIPK2 on the risk of severe radiation pneumonitis in lung cancer patients treated with radiation therapy

CharacteristicNo. of Patients%
Sex
 Male12574.0
 Female4426.0
Age, years
 Median58 
 Range28–78 
Histology
 SCLC5532.5
 NSCLC11467.5
Stage
 I- II2410.2
 III-IV14585.8
KPS
 80–10012372.6
  < 804627.4
Smoking
 Smoker10662.0
 Non-smoker6338.0
Chemotherapy
 Yes16094.7
 No95.3
CRT
 Yes4426.0
 No12574.0
Surgery
 Yes8650.9
 No8349.1
IMRT
 Yes7946.7
 No9053.3
Radiation dose (cGy)
 Median5600 
 Range4500–6600 
MLD (cGy)
 Median1368 
 Range178–2017 
V20
 Median24.82 
 Range0–42.00 
COPD
 Yes1911.2
 No15088.8
  1. Abbreviations: KPS Kamofsky performance status; CRT concurrent chemoradiation; IMRT intensity-modulated radiation therapy; MLD mean lung dose; V20 volume of normal lung receiving 20 Gy or more radiation; COPD chronic obstructive pulmonary disease