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Table 1 Detailed clinical characteristics of the patients enrolled in this study (N = 169)

From: Impact of genetic variant of HIPK2 on the risk of severe radiation pneumonitis in lung cancer patients treated with radiation therapy

Characteristic

No. of Patients

%

Sex

 Male

125

74.0

 Female

44

26.0

Age, years

 Median

58

 

 Range

28–78

 

Histology

 SCLC

55

32.5

 NSCLC

114

67.5

Stage

 I- II

24

10.2

 III-IV

145

85.8

KPS

 80–100

123

72.6

  < 80

46

27.4

Smoking

 Smoker

106

62.0

 Non-smoker

63

38.0

Chemotherapy

 Yes

160

94.7

 No

9

5.3

CRT

 Yes

44

26.0

 No

125

74.0

Surgery

 Yes

86

50.9

 No

83

49.1

IMRT

 Yes

79

46.7

 No

90

53.3

Radiation dose (cGy)

 Median

5600

 

 Range

4500–6600

 

MLD (cGy)

 Median

1368

 

 Range

178–2017

 

V20

 Median

24.82

 

 Range

0–42.00

 

COPD

 Yes

19

11.2

 No

150

88.8

  1. Abbreviations: KPS Kamofsky performance status; CRT concurrent chemoradiation; IMRT intensity-modulated radiation therapy; MLD mean lung dose; V20 volume of normal lung receiving 20 Gy or more radiation; COPD chronic obstructive pulmonary disease