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Table 4 Toxicity profile for all patients

From: Therapeutic effect of whole brain radiotherapy on advanced NSCLC between EGFR TKI-naïve and TKI-resistant

Side effectsTKI-naïve (%) (N = 207)TKI-resistant (N = 137)
All grades, N. (%)Grade III/IV, N. (%)All grades, N. (%)Grade III/IV, N. (%)
Fatigue117 (56.5)19 (9.1)81 (59.1)14 (10.2)
Anorexia84 (40.5)18 (8.7)56 (40.9)10 (7.3)
Diarrhea23 (11.1)4 (0.2)12 (8.8)1 (0.7)
Nausea142 (68.6)38 (18.4)95 (69.3)23 (16.8)
Vomiting134 (64.7)15 (7.2)83 (60.6)15 (10.9)
Headache105 (50.7)14 (6.8)51 (37.2)12 (8.8)
Anemia113 (54.6)5 (2.4)75 (54.1)3 (2.2)
Neutropenia95 (45.9)17 (8.2)69 (50.4)11 (8.0)
Thrombocytopenia88 (42.5)6 (2.9)62 (45.3)2 (1.5)
  1. Abbreviations: TKI tyrosine kinase inhibitors