TY - JOUR AU - Chen, W. AU - Zhang, S. AU - Zou, X. PY - 2010 DA - 2010// TI - Estimation and projection of lung cancer incidence and mortality in China JO - Zhongguo Fei Ai Za Zhi VL - 13 ID - Chen2010 ER - TY - JOUR AU - Steuer, C. E. AU - Ramalingam, S. S. PY - 2015 DA - 2015// TI - Targeting EGFR in lung cancer: lessons learned and future perspectives JO - Mol Asp Med VL - 45 UR - https://doi.org/10.1016/j.mam.2015.05.004 DO - 10.1016/j.mam.2015.05.004 ID - Steuer2015 ER - TY - JOUR AU - Lukas, R. V. AU - Wainwright, D. A. AU - Laterra, J. J. PY - 2016 DA - 2016// TI - Updates from the Neuro-oncology section of the 2015 American neurological association annual meeting JO - Future Oncol VL - 12 UR - https://doi.org/10.2217/fon.15.299 DO - 10.2217/fon.15.299 ID - Lukas2016 ER - TY - JOUR AU - Venur, V. A. AU - Ahluwalia, M. S. PY - 2015 DA - 2015// TI - Prognostic scores for brain metastasis patients: use in clinical practice and trial design JO - Chin Clin Oncol VL - 4 ID - Venur2015 ER - TY - JOUR AU - Bilous, M. AU - Serdjebi, C. AU - Boyer, A. AU - Tomasini, P. AU - Pouypoudat, C. PY - 2019 DA - 2019// TI - Quantitative mathematical modeling of clinical brain metastasis dynamics in non-small cell lung cancer JO - Sci Rep VL - 9 UR - https://doi.org/10.1038/s41598-019-49407-3 DO - 10.1038/s41598-019-49407-3 ID - Bilous2019 ER - TY - JOUR AU - Huang, Q. AU - Ouyang, X. PY - 2013 DA - 2013// TI - Predictive biochemical-markers for the development of brain metastases from lung cancer: clinical evidence and future directions JO - Cancer Epidemiol VL - 37 UR - https://doi.org/10.1016/j.canep.2013.06.003 DO - 10.1016/j.canep.2013.06.003 ID - Huang2013 ER - TY - JOUR AU - Khuntia, D. AU - Brown, P. AU - Li, J. AU - Mehta, M. P. PY - 2006 DA - 2006// TI - Whole-brain radiotherapy in the management of brain metastasis JO - J Clin Oncol VL - 24 UR - https://doi.org/10.1200/JCO.2005.04.6185 DO - 10.1200/JCO.2005.04.6185 ID - Khuntia2006 ER - TY - JOUR AU - Chen, K. AU - Yu, X. AU - Zhang, F. AU - Xu, Y. AU - Zhang, P. PY - 2018 DA - 2018// TI - Applicability of the lung-molGPA index in non-small cell lung cancer patients with different gene alterations and brain metastases JO - Lung Cancer VL - 125 UR - https://doi.org/10.1016/j.lungcan.2018.08.023 DO - 10.1016/j.lungcan.2018.08.023 ID - Chen2018 ER - TY - JOUR AU - Porta, R. AU - Sánchez-Torres, J. M. AU - Paz-Ares, L. AU - Massutí, B. AU - Reguart, N. AU - Mayo, C. PY - 2011 DA - 2011// TI - Brain metastases from lung cancer responding to erlotinib: the importance of EGFR mutation JO - Eur Respir J VL - 37 UR - https://doi.org/10.1183/09031936.00195609 DO - 10.1183/09031936.00195609 ID - Porta2011 ER - TY - JOUR AU - Zeng, Y. D. AU - Liao, H. AU - Qin, T. AU - Zhang, L. AU - Wei, W. D. AU - Liang, J. Z. PY - 2015 DA - 2015// TI - Blood-brain barrier permeability of gefitinib in patients with brain metastases from non-small-cell lung cancer before and during whole brain radiation therapy JO - Oncotarget VL - 6 UR - https://doi.org/10.18632/oncotarget.3187 DO - 10.18632/oncotarget.3187 ID - Zeng2015 ER - TY - JOUR AU - Jackman, D. AU - Pao, W. AU - Riely, G. J. AU - Engelman, J. A. AU - Kris, M. G. AU - Jänne, P. A. PY - 2010 DA - 2010// TI - Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer JO - J Clin Oncol VL - 28 UR - https://doi.org/10.1200/JCO.2009.24.7049 DO - 10.1200/JCO.2009.24.7049 ID - Jackman2010 ER - TY - JOUR AU - Lee, Y. J. AU - Choi, H. J. AU - Kim, S. K. AU - Chang, J. AU - Moon, J. W. AU - Park, I. K. PY - 2010 DA - 2010// TI - Frequent central nervous system failure after clinical benefit with epidermal growth factor receptor tyrosine kinase inhibitors in Korean patients with nonsmall-cell lung cancer JO - Cancer VL - 116 UR - https://doi.org/10.1002/cncr.24877 DO - 10.1002/cncr.24877 ID - Lee2010 ER - TY - JOUR AU - Wang, C. AU - Lu, X. AU - Lyu, Z. AU - Bi, N. AU - Wang, L. PY - 2018 DA - 2018// TI - Comparison of up-front radiotherapy and TKI with TKI alone for NSCLC with brain metastases and EGFR mutation: A meta-analysis JO - Lung Cancer VL - 122 UR - https://doi.org/10.1016/j.lungcan.2018.05.014 DO - 10.1016/j.lungcan.2018.05.014 ID - Wang2018 ER - TY - BOOK AU - Young, K. PY - 2008 DA - 2008// TI - Palliation of brain and spinal cord metastases in Perez and Brady's principles and practice of radiation oncology PB - Wilkins CY - Philadelphia ID - Young2008 ER - TY - JOUR AU - Gaspar, L. AU - Scott, C. AU - Rotman, M. AU - Asbell, S. AU - Phillips, T. AU - Wasserman, T. PY - 1997 DA - 1997// TI - Recursive partitioning analysis (RPA) of prognostic factors in three radiation therapy oncology group (RTOG) brain metastases trials JO - Int J Radiat Oncol Biol Phys VL - 37 UR - https://doi.org/10.1016/S0360-3016(96)00619-0 DO - 10.1016/S0360-3016(96)00619-0 ID - Gaspar1997 ER - TY - JOUR AU - Knisely, J. P. AU - Berkey, B. AU - Chakravarti, A. AU - Yung, A. W. AU - Curran, W. J. AU - Robins, H. I. PY - 2008 DA - 2008// TI - A phase III study of conventional radiation therapy plus thalidomide versus conventional radiation therapy for multiple brain metastases (RTOG 0118) JO - Int J Radiat Oncol Biol Phys VL - 71 UR - https://doi.org/10.1016/j.ijrobp.2007.09.016 DO - 10.1016/j.ijrobp.2007.09.016 ID - Knisely2008 ER - TY - JOUR AU - Das, A. K. AU - Sato, M. AU - Story, M. D. AU - Peyton, M. AU - Graves, R. AU - Redpath, S. PY - 2016 DA - 2016// TI - Nonsmall cell lung cancers with kinase domain mutations in the epidermal growth factor receptor are sensitive to ionizing radiation JO - Cancer Res VL - 66 UR - https://doi.org/10.1158/0008-5472.CAN-06-2627 DO - 10.1158/0008-5472.CAN-06-2627 ID - Das2016 ER - TY - JOUR AU - Lee, H. L. AU - Chung, T. S. AU - Ting, L. L. AU - Tsai, J. T. AU - Chen, S. W. AU - Chiou, J. F. PY - 2012 DA - 2012// TI - EGFR mutations are associated with favorable intracranial response and progression-free survival following brain irradiation in non-small cell lung cancer patients with brain metastases JO - Radiat Oncol VL - 7 UR - https://doi.org/10.1186/1748-717X-7-181 DO - 10.1186/1748-717X-7-181 ID - Lee2012 ER - TY - JOUR AU - Sperduto, P. W. AU - Yang, T. J. AU - Beal, K. AU - Pan, H. AU - Brown, P. D. AU - Bangdiwala, A. PY - 2017 DA - 2017// TI - Estimating survival in patients with lung cancer and brain metastases: An update of the graded prognostic assessment for lung cancer using molecular markers (lung-molGPA) JO - JAMA Oncol VL - 3 UR - https://doi.org/10.1001/jamaoncol.2016.3834 DO - 10.1001/jamaoncol.2016.3834 ID - Sperduto2017 ER - TY - JOUR AU - Huang, S. M. AU - Li, J. AU - Armstrong, E. A. AU - Harari, P. M. PY - 2001 DA - 2001// TI - Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa) JO - Cancer Res VL - 62 ID - Huang2001 ER - TY - JOUR AU - Chinnaiyan, P. AU - Huang, S. AU - Vallabhaneni, G. AU - Armstrong, E. AU - Varambally, S. AU - Tomlins, S. A. PY - 2005 DA - 2005// TI - Mechanisms of enhanced radiation response following epidermal growth factor receptor signaling inhibition by erlotinib (Tarceva) JO - Cancer Res VL - 65 UR - https://doi.org/10.1158/0008-5472.CAN-04-3547 DO - 10.1158/0008-5472.CAN-04-3547 ID - Chinnaiyan2005 ER - TY - JOUR AU - Milas, L. AU - Mason, K. AU - Hunter, N. AU - Petersen, S. AU - Yamakawa, M. AU - Ang, K. PY - 2000 DA - 2000// TI - In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody JO - Clin Cancer Res VL - 6 ID - Milas2000 ER - TY - JOUR AU - Kosaka, T. AU - Yamaki, E. AU - Mogi, A. AU - Kuwano, H. PY - 2011 DA - 2011// TI - Mechanisms of resistance to EGFR TKIs and development of a new generation of drugs in non-small cell lung cancer JO - J Biomed Biotechnol VL - 2011 UR - https://doi.org/10.1155/2011/165214 DO - 10.1155/2011/165214 ID - Kosaka2011 ER - TY - JOUR AU - Yang, J. J. AU - Zhou, C. AU - Huang, Y. AU - Feng, J. AU - Lu, S. AU - Song, Y. PY - 2017 DA - 2017// TI - Icotinib versus whole-brain irradiation in patients with EGFR-mutant non-small-cell lung cancer and multiple brain metastases (BRAIN): a multicentre, phase 3, open-label, parallel, randomised controlled trial JO - Lancet Respir Med VL - 5 UR - https://doi.org/10.1016/S2213-2600(17)30262-X DO - 10.1016/S2213-2600(17)30262-X ID - Yang2017 ER - TY - JOUR AU - An, N. AU - Wang, H. AU - Li, J. AU - Zhai, X. AU - Jing, W. PY - 2019 DA - 2019// TI - Therapeutic effect of first-line EGFR-TKIs combined with concurrent cranial radiotherapy on NSCLC patients with EGFR activating mutation and brain metastasis: a retrospective study JO - Onco Targets Ther VL - 12 UR - https://doi.org/10.2147/OTT.S223216 DO - 10.2147/OTT.S223216 ID - An2019 ER - TY - JOUR AU - Yu, H. A. AU - Sima, C. S. AU - Huang, J. AU - Solomon, S. B. AU - Rimner, A. AU - Paik, P. PY - 2013 DA - 2013// TI - Local therapy with continued EGFR tyrosine kinase inhibitor therapy as a treatment strategy in EGFR-mutant advanced lung cancers that have developed acquired resistance to EGFR tyrosine kinase inhibitors JO - J Thorac Oncol VL - 8 UR - https://doi.org/10.1097/JTO.0b013e31827e1f83 DO - 10.1097/JTO.0b013e31827e1f83 ID - Yu2013 ER - TY - JOUR AU - Javvadi, P. AU - Makino, H. AU - Das, A. K. AU - Lin, Y. F. AU - Chen, D. J. AU - Chen, B. P. PY - 2012 DA - 2012// TI - Threonine 2609 phosphorylation of the DNA-dependent protein kinase is a critical prerequisite for epidermal growth factor receptor-mediated radiation resistance JO - Mol Cancer Res VL - 10 UR - https://doi.org/10.1158/1541-7786.MCR-12-0482-T DO - 10.1158/1541-7786.MCR-12-0482-T ID - Javvadi2012 ER - TY - JOUR AU - Fleur, L. AU - Johansson, A. C. AU - Roberg, K. PY - 2012 DA - 2012// TI - A CD44high/EGFRlow subpopulation within head and neck cancer cell lines shows an epithelial-mesenchymal transition phenotype and resistance to treatment JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0044071 DO - 10.1371/journal.pone.0044071 ID - Fleur2012 ER - TY - JOUR AU - Magnuson, W. J. AU - Yeung, J. T. AU - Guillod, P. D. AU - Gettinger, S. N. AU - Yu, J. B. AU - Chiang, V. L. PY - 2016 DA - 2016// TI - Impact of deferring radiation therapy in patients with epidermal growth factor receptor-mutant non-small cell lung Cancer who develop brain metastases JO - Int J Radiat Oncol Biol Phys VL - 95 UR - https://doi.org/10.1016/j.ijrobp.2016.01.037 DO - 10.1016/j.ijrobp.2016.01.037 ID - Magnuson2016 ER - TY - JOUR AU - Chen AU - Lee AU - Chuang AU - Hung AU - Huang AU - Chong PY - 2019 DA - 2019// TI - Combination of Whole-Brain Radiotherapy with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors Improves Overall Survival in EGFR-Mutated Non-Small Cell Lung Cancer Patients with Brain Metastases JO - Cancers VL - 11 UR - https://doi.org/10.3390/cancers11081092 DO - 10.3390/cancers11081092 ID - Chen2019 ER - TY - JOUR AU - Li, C. AU - Guo, J. AU - Zhao, L. AU - Hu, F. AU - Nie, W. PY - 2019 DA - 2019// TI - Upfront whole brain radiotherapy for multiple brain metastases in patients with EGFR-mutant lungadenocarcinoma JO - Cancer Manag Res VL - 11 ID - Li2019 ER - TY - JOUR AU - Wang, N. AU - Wang, L. AU - Meng, X. AU - Wang, J. AU - Zhu, L. AU - Liu, C. PY - 2019 DA - 2019// TI - Osimertinib (AZD9291) increases radio-sensitivity in EGFR T790M non-small cell lung cancer JO - Oncol Rep VL - 41 ID - Wang2019 ER -