Table 5 univariate and multivariate analysis of local control
Local control | p-value | |||
|---|---|---|---|---|
at 12 months (%) | at 24 months (%) | univariate Analysis | multivariate Analysis | |
Age | ||||
65 years | 58 | 58 | ||
> 65 years | 83 | 63 | 0.380 | |
Gender | ||||
Female | 68 | 57 | ||
Male | 80 | 80 | 0.941 | |
Karnofsky performance status | ||||
> 80% | 73 | 67 | ||
≤ 80% | 66 | 33 | 0.233 | |
UICC stage | ||||
III | 66 | 62 | ||
IV | 100 | 67 | 0.862 | |
T category | ||||
1–2 | 66 | 62 | ||
3–4 | 100 | 67 | 0.970 | |
N category | ||||
0–1 | 33 | 33 | ||
2–3 | 75 | 64 | 0.154 | |
Histology | ||||
Squamous cell carcinoma | 70 | 60 | ||
Non- Squamous cell carcinoma | 70 | 62 | 0.766 | |
Tobacco consumption (PY) | ||||
0 | 83 | 83 | ||
20–40 | 51 | 34 | ||
> 40 | 72 | 60 | 0.417 | |
Grading | ||||
Moderately differentiated | 100 | 100 | ||
Poorly differentiated | 70 | 59 | ||
anaplastic | 50 | 50 | 0.487 | |
PD-L1 expression | ||||
0% | 92 | 79 | ||
≥ 1% | 44 | 44 | 0.017 | 0.045 |
CD8+ TILs density | ||||
≤ 40% | 86 | 75 | ||
> 40% | 62 | 62 | 0.092 | |
TIME type | ||||
I | 100 | 80 | ||
II | 41 | 41 | ||
III | 83 | 83 | ||
IV | 67 | 67 | 0.05 | 0.694 |