Table 4 univariate and multivariate survival analysis
Survival | p-value | |||
|---|---|---|---|---|
at 12 months (%) | at 24 months (%) | univariate Analysis | multivariate Analysis | |
Age | ||||
≤ 65 years | 56 | 19 | ||
> 65 years | 80 | 27 | 0.676 | |
Gender | ||||
Female | 80 | 20 | ||
Male | 65 | 23 | 0.629 | |
Karnofsky performance status | ||||
> 80% | 75 | 30 | ||
≤ 80% | 55 | 10 | 0.041 | 0.077 |
UICC stage | ||||
III | 64 | 21 | ||
IV | 100 | 33 | 0.537 | |
T category | ||||
1–2 | 67 | 0 | ||
3–4 | 68 | 28 | 0.395 | |
N category | ||||
0–1 | 33 | 0 | ||
2–3 | 71 | 25 | 0.299 | |
Histology | ||||
Squamous cell carcinoma | 69 | 25 | ||
Non- Squamous cell carcinoma | 67 | 20 | 0.935 | |
Tobacco consumption (PY) | ||||
0 | 75 | 25 | ||
20–40 | 50 | 12,50 | ||
> 40 | 73 | 27 | 0.758 | |
Grading | ||||
Moderately differentiated | 50 | 50 | ||
Poorly differentiated | 67 | 19 | ||
anaplastic | 100 | 50 | 0.758 | |
PD-L1 expression | ||||
0% | 86 | 29 | ||
≥ 1% | 50 | 19 | 0.048 | 0.648 |
CD8+ TILs density | ||||
≤ 40% | 70 | 40 | ||
> 40% | 61 | 17 | 0.055 | |
TIME type | ||||
I | 100 | 60 | ||
II | 50 | 20 | ||
III | 71 | 14 | ||
IV | 40 | 20 | 0.05 | 0.048 |