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Table 2 Correlations of PD-L1 expression and clinicopathologic characteristics

From: Prognostic value of PD-L1 expression on tumor cells combined with CD8+ TIL density in patients with locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy

  Positive, n (%) Negative, n (%) p-value
Age
  ≤ 65 years 8 (50) 8 (50)  
  > 65 years 8 (57) 6 (43) 0.834
Gender
 Female 13 (52) 12 (48)  
 Male 4 (80) 1 (20) 0.513
Karnofsky performance status
 90–100% 8 (80) 2 (20)  
 70–80% 8 (40) 12 (60) 0.023
UICC stage
 III 15 (56) 12 (44)  
 IV 1 (33) 2 (67) 0.447
T category
 1–2 4 (67) 2 (33)  
 3–4 12 (50) 12 (50) 0.073
N category
 0–1 2 (67) 1 (33)  
 2–3 14 (52) 13 (48) 0.402
Histology
 Squamous cell carcinoma 9 (60) 6 (40)  
 Non- Squamous cell carcinoma 7 (47) 8 (53) 0.864
Tobacco consumption (PY)
 0 5 (63) 3 (38)  
 20–40 3 (38) 5 (63)  
  > 40 8 (57) 6 (43) 0.105
Grading
 Moderately differentiated 1 (50) 1 (50)  
 Poorly differentiated 14 (54) 12 (46)  
 anaplastic 1 (50) 1 (50) 0.223
CD8+ TILs density
  ≤ 40% 5 (50) 5 (50)  
  > 40% 10 (59) 7 (41) 0.020