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Table 5 Relationship between tumor location and outcome in the literature

From: Tumor burden and location as prognostic factors in patients treated by iodine seed implant brachytherapy for localized prostate cancers

 

Period of recruitment

Number of patients

Median number of biopsy cores

Tumor location

Median follow-up

Outcome

Samuelian et al., 2011 [65]

1998–2006

52

7

BI: 52

89 months

10-year bPFS = 93.5%

Hill et al., 2015 [60]

1998–2012

846

12

BI: 528

MI: 578

AI: 560

Non BI: 318

5.59 years

Biochemical failures: 62 (7.3%)

BI: 42/62 (67.7%)

No BI: 20/62 (32.3%)

(p = 0.17)

Present study

2006–2013

282

12

BI: 145

MI: 149

AI: 131

61 months

Biochemical failures: 20 (7.1%)

Failures: BI 11patients (55%) / MI 10 (50%) / AI 10 (50%)

Non failures: BI 134 patients (51.1%)/ MI 139 (53.1%)/ AI 121 (46.2%)

NS

  1. Abbreviations: BI base involvement, MI midgland involvement, AI apex involvement