Table 2 Association of RP with dose-volume variables
Gemcitabine | Docetaxel | |||||||
|---|---|---|---|---|---|---|---|---|
Variable | n | Grade ≥ 2 RP, n(%) | Hazard Ratio | P | n | Grade ≥ 2 RP, n(%) | Hazard Ratio | P |
Lung V5 | ||||||||
≤ 44 | 95 | 14 | 1 | 0.001 | 65 | 8 | 1 | 0.781 |
>44 | 89 | 33 | 3.41 (1.67–6.95) | 79 | 11 | 1.15 (0.43–3.06) | ||
Lung V20 | ||||||||
≤ 24 | 114 | 18 | 1 | <0.001 | 73 | 7 | 1 | 0.200 |
>24 | 70 | 29 | 3.77 (1.89–7.54) | 71 | 12 | 1.92 (0.71–5.19) | ||
Lung V30 | ||||||||
≤ 14.2 | 71 | 9 | 1 | 0.002 | 52 | 4 | 1 | 0.151 |
>14.2 | 113 | 38 | 3.49 (1.57–7.77) | 92 | 15 | 2.34 (0.73–7.46) | ||
MLD | ||||||||
≤ 1226 cGy | 106 | 17 | 1 | 0.001 | 58 | 4 | 1 | 0.076 |
>1226 cGy | 78 | 30 | 3.27 (1.64–6.53) | 86 | 15 | 2.85 (0.90–9.08) | ||