Skip to main content

Table 1 The relationship between patients’ characteristics and chemotherapy regimens

From: Risk factors of grade ≥ 2 radiation pneumonitis after gemcitabine induction chemotherapy for patients with non-small cell lung cancer

Variables

N

Gemcitabine

Docetaxel

P

Gender

 Female

28

15(53.6)

13(46.4)

0.843

 Male

300

169(56.3)

131(43.7)

 

Age

 <65

210

112(53.3)

98(46.7)

0.203

  ≥ 65

118

72(61.0)

46(39.0)

 

Tumor location

 Left

145

85(58.6)

60(41.4)

0.434

 Right

183

99(54.1)

84(45.9)

 

Histology

 SCC

242

140(57.9)

102(42.1)

0.482

 Ade

59

29(49.2)

30(50.8)

 

 Others

27

15(55.6)

12(44.4)

 

Concurrent CRT

 Yes

253

146(57.7)

107(42.3)

0.281

 No

75

38(50.7)

37(49.3)

 

T stage

 T1–2

187

107(57.2)

80(42.8)

0.637

 T3–4

141

77(54.6)

64(45.4)

 

N stage

 N0–1

64

42(65.6)

22(34.4)

0.087

 N2–3

264

142(53.8)

122(46.2)

 

PTV volume

 ≤ 330 cc

164

95(57.9)

69(42.1)

0.504

 >330 cc

164

89(54.3)

75(45.7)

 

Lung volume

 ≤ 3248 cc

177

101(57.1)

76(42.9)

0.703

 >3248 cc

151

83(55.0)

68(45.0)

 

V5

 ≤ 44

160

95 (59.4)

65 (40.6)

0.243

 >44

168

89 (53.0)

79 (47.0)

 

V20

  ≤ 24

187

114 (61.0)

73 (39.0)

0.041

 >24

141

70 (49.6)

71 (50.4)

 

V30

 ≤ 14.2

122

71 (57.4)

52 (42.6)

0.691

 >14.2

205

113 (55.1)

92 (44.9)

 

MLD

 ≤ 1226 cGy

164

106 (64.6)

58 (35.4)

0.002

 >1266 cGy

164

78 (47.6)

86 (52.4)

 

RP

 1

262

137(52.3)

125(47.7)

0.006

 2

49

32(65.3)

17(34.7)

 

 3–4

17

15(88.2)

2(11.8)

 
  1. CRT Chemoradiotherapy, MLD Meal lung dose, RP Radiation Pneumonitis