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Table 3 Average deviations of LEM-predictions from experimental data. Values are given as mean ± 1 SD (A, B, D) or ± 1 SE (C), respectively

From: Fractionated carbon ion irradiations of the rat spinal cord: comparison of the relative biological effectiveness with predictions of the local effect model

 LEM ILEM IV
(A) FxRBE-deviation averaged over SOBP regionc [%]
1-20.7 ± 5.1−6.6 ± 3.9
2−19.9 ± 6.3− 7.0 ± 4.1
6−19.9 ± 7.9−11.3 ± 7.6
∞ (limit d➔0)a− 1.7 ± 25.54.8 ± 22.3
(B) FxRBE-deviation averaged over entrance regionb [%]
1−11.2 ± 1.9−17.8 ± 1.0
2−7.5 ± 3.8−19.7 ± 3.0
6−3.0 ± 4.3−26.9 ± 3.1
∞ (limit d➔0)a58.6 ± 27.2−49.2 ± 2.2
(C) FxSlope ratio in SOBP regionc
10.37 ± 0.081.27 ± 0.21
20.44 ± 0.041.17 ± 0.08
60.51 ± 0.181.19 ± 0.35
∞ (limit d➔0)a0.36 ± 0.121.68 ± 0.53
(D) LET [keV/μm]RBE-deviation averaged over 1, 2 and 6 fractions [%]
16−4.9 ± 4.9− 19.8 ± 4.3
21− 9.6 ± 3.3− 23.1 ± 5.4
36−13.2 ± 1.0−11.4 ± 4.3
45− 16.9 ± 3.0−10.9 ± 0.7
66−23.7 ± 3.0− 9.8 ± 6.0
99−26.7 ± 0.8− 1.1 ± 0.6
  1. a Values obtained from RBEmax
  2. b Data points at 16 and 21 keV/μm
  3. c Data points at 36, 45, 66 and 99 keV/μm