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Table 3 Average deviations of LEM-predictions from experimental data. Values are given as mean ± 1 SD (A, B, D) or ± 1 SE (C), respectively

From: Fractionated carbon ion irradiations of the rat spinal cord: comparison of the relative biological effectiveness with predictions of the local effect model

 

LEM I

LEM IV

(A) Fx

RBE-deviation averaged over SOBP regionc [%]

1

-20.7 ± 5.1

−6.6 ± 3.9

2

−19.9 ± 6.3

− 7.0 ± 4.1

6

−19.9 ± 7.9

−11.3 ± 7.6

∞ (limit d➔0)a

− 1.7 ± 25.5

4.8 ± 22.3

(B) Fx

RBE-deviation averaged over entrance regionb [%]

1

−11.2 ± 1.9

−17.8 ± 1.0

2

−7.5 ± 3.8

−19.7 ± 3.0

6

−3.0 ± 4.3

−26.9 ± 3.1

∞ (limit d➔0)a

58.6 ± 27.2

−49.2 ± 2.2

(C) Fx

Slope ratio in SOBP regionc

1

0.37 ± 0.08

1.27 ± 0.21

2

0.44 ± 0.04

1.17 ± 0.08

6

0.51 ± 0.18

1.19 ± 0.35

∞ (limit d➔0)a

0.36 ± 0.12

1.68 ± 0.53

(D) LET [keV/μm]

RBE-deviation averaged over 1, 2 and 6 fractions [%]

16

−4.9 ± 4.9

− 19.8 ± 4.3

21

− 9.6 ± 3.3

− 23.1 ± 5.4

36

−13.2 ± 1.0

−11.4 ± 4.3

45

− 16.9 ± 3.0

−10.9 ± 0.7

66

−23.7 ± 3.0

− 9.8 ± 6.0

99

−26.7 ± 0.8

− 1.1 ± 0.6

  1. a Values obtained from RBEmax
  2. b Data points at 16 and 21 keV/μm
  3. c Data points at 36, 45, 66 and 99 keV/μm