Skip to main content

Table 2 Determined values for TD50, BED50, RBE, RBEmax and α/β together with the single standard errors (SE) and 90%-confidence limits (CL)

From: Fractionated carbon ion irradiations of the rat spinal cord: comparison of the relative biological effectiveness with predictions of the local effect model

StudyTD50 ± SE (90% CL) [Gy]RBE ± SE (90% CL)
(A) 6 Fx
 Photonsa57.0 ± 2.0 (−)b 
 Carbon ions
  16 keV/μm39.1 ± 0.4 (38.2–40.0)1.46 ± 0.05 (1.37–1.55)
  21 keV/μm33.8 ± 0.6 (32.5–35.0)1.69 ± 0.07 (1.58–1.80)
  36 keV/μm28.7 ± 1.5 (−)b1.98 ± 0.12 (1.79–2.21)
  45 keV/μm26.9 ± 0.5 (25.7–28.1)2.12 ± 0.08 (1.98–2.26)
  66 keV/μm18.6 ± 0.4 (17.8–19.3)3.07 ± 0.12 (2.87–3.27)
  99 keV/μm17.5 ± 0.3 (16.8–18.2)3.26 ± 0.13 (3.05–3.48)
(B) 1, 2 and 6 FxBED50 ± SE (90% CL) [Gy]RBEmax ± SE (90% CL)
 Photonsa244.9 ± 24.3 (208.2–293.3) 
 Carbon ions
  16 keV/μm76.3 ± 7.2 (66.0–92.0)3.21 ± 0.44 (2.55–4.02)
  21 keV/μm53.3 ± 3.7 (47.7–60.9)4.59 ± 0.55 (3.73–5.57)
  36 keV/μm39.5 ± 2.3 (36.0–44.6)6.21 ± 0.71 (5.09–7.44)
  45 keV/μm36.4 ± 1.8 (33.2–40.3)6.73 ± 0.74 (5.55–8.00)
  66 keV/μm20.3 ± 0.6 (19.4–21.3)12.07 ± 1.24 (10.05–14.13)
  99 keV/μm19.0 ± 0.6 (18.1–20.1)12.87 ± 1.33 (10.71–15.08)
(C) 1, 2 and 6 Fxα/β ± SE (90% CL) [Gy] 
 Photonsa2.8 ± 0.4 (2.2–3.5) 
 Carbon ions
  16 keV/μm6.9 ± 1.1 (5.2–8.9) 
  21 keV/μm9.8 ± 1.3 (7.7–12.2) 
  36 keV/μm14.6 ± 1.9 (11.4–18.2) 
  45 keV/μm12.8 ± 1.5 (10.3–16.4) 
  66 keV/μm44.3 ± 7.2 (33.8–60.4) 
  99 keV/μm30.8 ± 4.6 (23.9–40.9) 
  1. aData obtained or derived from [10]
  2. bEstimated standard error, confidence limits could not be determined (see text)