Table 1 Dose-volume metrics for DIBH and FB treatment plans
Metric | Breast Only | Breast + SC only | Breast + RNI | ||||||
|---|---|---|---|---|---|---|---|---|---|
FB | DIBH | P value | FB | DIBH | P value | FB | DIBH | P value | |
CTV | |||||||||
 Mean (Gy) | 40.9 ± 0.4 | 40.9 ± 0.4 | 0.6 | 40.9 ± 0.3 | 40.8 ± 0.3 | 0.8 | 40.6 ± 0.2 | 40.6 ± 0.2 | 0.5 |
 V95% (%) | 99.4 ± 0.7 | 99.5 ± 0.8 | 1 | 99.4 ± 0.4 | 98.7 ± 1.5 | 0.3 | 100.0 ± 0.03 | 99.9 ± 0.2 | 1 |
Lung (total) | |||||||||
 Mean (Gy) | 2.4 ± 0.5 | 2.3 ± 0.8 | 0.3 | 3.5 ± 0.5 | 3.1 ± 0.5 | 0.01 | 10.8 ± 1.7 | 8.9 ± 1.2 | 0.002 |
 V20Gy (%) | 4.1 ± 0.5 | 4.0 ± 1.9 | 0.4 | 6.7 ± 1.2 | 5.4 ± 1.2 | 0.02 | 25.2 ± 7.6 | 17.9 ± 5.1 | 0.002 |
 V5Gy (%) | 9.6 ± 2.3 | 8.7 ± 3.2 | 0.3 | 13.9 ± 2.3 | 12.4 ± 1.6 | 0.02 | 51.0 ± 3.5 | 47.4 ± 3.2 | 0.004 |
 Volume (cm3) | 2613.2 ± 728.1 | 4467.6 ± 649.0 | 0.001 | 2714.8 ± 595.0 | 4452.0 ± 591.5 | 0.001 | 2714.8 ± 595.0 | 4452.0 ± 591.5 | 0.001 |
Lung (ipsilateral) | |||||||||
 Mean (Gy) | 4.4 ± 1.0 | 4.3 ± 1.5 | 0.4 | 6.3 ± 0.9 | 5.6 ± 0.9 | 0.05 | 18.9 ± 3.2 | 15.9 ± 2.3 | 0.002 |
 V20Gy (%) | 7.6 ± 2.3 | 7.5 ± 3.6 | 0.4 | 12.0 ± 2.2 | 9.8 ± 2.2 | 0.03 | 45.3 ± 13.3 | 32.9 ± 9.4 | 0.002 |
 V5Gy (%) | 17.6 ± 4.3 | 16.4 ± 6.0 | 0.3 | 25.1 ± 4.0 | 22.7 ± 3.1 | 0.06 | 91.6 ± 5.6 | 86.7 ± 7.1 | 0.01 |
Liver | |||||||||
 Max. (Gy) | 22.3 ± 15.7 | 9.2 ± 13.6 | 0.006 | 32.4 ± 11.0 | 10.4 ± 10.8 | 0.001 | 31.3 ± 13.3 | 15.3 ± 9.8 | 0.002 |
 V20Gy (cc) | 9.2 ± 18.9 | 1.8 ± 5.6 | 0.03 | 10.8 ± 17.2 | 0.8 ± 2.6 | 0.001 | 24.3 ± 38.4 | 0.8 ± 2.2 | 0.02 |
Heart | |||||||||
 Mean (Gy) | 0.2 ± 0.1 | 0.2 ± 0.1 | 0.7 | 0.3 ± 0.1 | 0.4 ± 0.1 | 0.2 | 2.6 ± 0.8 | 2.1 ± 0.7 | 0.09 |
 Max. (Gy) | 2.4 ± 0.5 | 2.5 ± 0.4 | 0.5 | 1.6 ± 0.5 | 1.7 ± 0.4 | 0.9 | 27.8 ± 7.6 | 21.5 ± 6.6 | 0.02 |
LAD | |||||||||
 Mean (Gy) | 0.03 ± 0.02 | 0.03 ± 0.02 | 0.7 | 0.1 ± 0.04 | 0.1 ± 0.03 | 0.2 | 0.5 ± 0.2 | 0.6 ± 0.2 | 0.1 |
 Max (Gy) | 0.1 ± 0.1 | 0.1 ± 0.1 | 0.4 | 0.2 ± 0.1 | 0.2 ± 0.1 | 0.1 | 1.2 ± 0.8 | 1.2 ± 0.7 | 0.9 |
RCA | |||||||||
 Mean (Gy) | 0.7 ± 0.3 | 0.6 ± 0.3 | 0.4 | 0.9 ± 0.2 | 1.0 ± 0.4 | 0.5 | 5.0 ± 2.5 | 3.5 ± 1.9 | 0.1 |
 Max (Gy) | 1.1 ± 0.4 | 1.0 ± 0.5 | 0.5 | 1.6 ± 0.5 | 1.7 ± 0.4 | 0.7 | 11.6 ± 7.2 | 5.6 ± 2.9 | 0.03 |