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Table 1 Baseline characteristics of 72 patients with locally advanced head and neck squamous cell carcinoma according to whether they achieved pathological complete remission (pCR)

From: Prognostic impact of pathological complete remission after preoperative irradiation in patients with locally advanced head and neck squamous cell carcinoma: re-analysis of a phase 3 clinical study

Characteristic

pCR (n = 25)

Non-pCR (n = 47)

p-value

n

%

n

%

Gender

 Male

22

35.5

40

64.5

0.735

 Female

3

30.0

7

70.0

 

Median age (years)

55

 

55

  

Primary site

 Oral cavity

4

30.8

9

69.2

0.869

 Oropharynx

4

30.8

9

69.2

 

 Larynx/Hypopharynx

17

37.0

29

63.0

 

T stage

  T1

1

50.0

1

50.0

0.218

  T2

7

63.6

4

36.4

 

  T3

7

35.0

13

65.0

 

  T4a

9

26.5

25

73.5

 

  T4b

1

20.0

4

80.0

 

N stage

  N0

2

25.0

6

75.0

0.266

 N1

1

10.0

9

90.0

 

 N2

18

40.9

26

59.1

 

 N3

4

40.0

6

60.0

 

Clinical group

 III

1

14.3

6

85.7

0.463

 IVA

9

22.5

31

77.5

 

 IVB

5

33.3

10

66.7

 

Concurrent chemotherapy

  Yes

10

27.0

27

73.0

0.158

  No

15

42.9

20

57.1

 

Radiotherapy technique

 2D

14

29.8

33

70.2

0.228

  IMRT

11

44.0

14

56.0

 
  1. 2D Two dimensional, IMRT Intensity-modulated radiotherapy