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Table 2 Results of the univariable Cox regression analysis. For variables with missing values, only known values were considered for model building

From: Accelerated hyperfractionated radiochemotherapy with temozolomide is equivalent to normofractionated radiochemotherapy in a retrospective analysis of patients with glioblastoma

VariableHR95% CIp
lowerhigher
RT-protocol NFRT vs HFRT1.3810.9062.1060.133
Age (continuous)1.0231.0071.0390.0052
Gender: Female vs. Male0.7000.4811.0190.062
Surgery extent:
Subtotal vs. complete resection1.2530.7971.9690.329
Debulking vs. complete resection1.1520.5572.3850.703
Biopsy vs. complete resection2.8131.7524.5161.87 × 10−5
Mental status: Impaired vs. Normal0.8090.4211.5540.524
Neurological function: Impaired vs. Normal1.0080.6711.5140.969
MGMT methylation: Yes vs. No0.2320.1330.4032.23 × 10−7
IDH mutation: Yes vs. No0.1670.0231.2110.0766
Secondary GBM: Yes vs. No0.3110.1430.6760.0032
PTV: >  269 ccm vs. ≤269 ccm1.7501.1682.6220.00668
Temozolomide: Yes vs. No0.5230.3550.7690.000984
Steroids: Yes vs. No2.2051.4713.3070.00013
Salvage: Yes vs. No0.2680.1800.4001.24 × 10−10
KPS:
70–80 vs. < 70
90–100 vs. < 70
0.786
0.706
0.426
0.386
1.447
1.292
0.440
0.259
Treatment period:
2008–2013 vs. 2004-20083.5911.11711.550.032
2014–2018 vs. 2004-20083.6621.11911.980.032
Tumor treating fields: Yes vs. No0.8360.3861.8090.649
  1. 0.005 P value entries are in bold