From: Oncologic and visual outcomes after postoperative proton therapy of localized conjunctival melanomas
Bivariate analysesa | Multivariate analysis a ∆ | |||
---|---|---|---|---|
Estimationâ—Š | p-value | Estimationâ—Š | p-value | |
female (vs. male) | 0.046(0.164) | 0.781 | ||
Age (years) | 0.010(0.005) | 0.072 | 0.01 (0.004) | 0.008 |
Precancerous lesion nevus vs. de novo PAM vs. de novo | 0.146(0.180) 0. 365 (0.184) | 0.423 0.052 | 0.243 (0.168) 0.285 (0.126) | 0.153 0.028 |
Clinical stage | ||||
 T2 vs. T1 | 0.040(0.214) | 0.853 | ||
 T3 vs. T1 | 0.524 (0.333) | 0.121 | ||
Pathological stage | ||||
 pT2 vs. pT1 | 0.031(0.203) | 0.880 | ||
 pT3 vs. pT1 | 0.723(0.375) | 0.059 | ||
Multifocal | 0.768(0.202) | < 0.001 | 0.554 (0.157) | < 0.001 |
Quandrangular involvement from 90 to 180° vs < 90° > 180° vs < 90° | 1.446(0.284) 0.246(0.146) | 0.098 < .001 | 0.176 (0.115) 0.954 (0.237) | 0.130 < 0.001 |
Epithelioid type | 0.123(0.166) | 0.461 | ||
Margins | ||||
 R1 vs.R0 | 0.041(0.181) | 0.8193 | ||
 R2 vs.R0 | −0.302(0.251) | 0.2329 | ||
Number of mitoses < 2 | −0.003(0.159) | 0.986 | ||
Ulceration | 0.197(0.236) | 0.407 | ||
Thickness < 2 mm | 0.147(0.248) | 0.556 | ||
Diameter < 7 mm | −.020(0.161) | 0.899 | ||
Cryotherapy | 0.585(0.149) | < 0.001 | 0.461 (0.11) | < 0.001 |
Mitomycin | −0.302(0.170) | 0.082 | ||
Follow-up time (years) | 0.007(0.013) | 0.607 |