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Fig. 4 | Radiation Oncology

Fig. 4

From: Time-synchronized immune-guided SBRT partial bulky tumor irradiation targeting hypoxic segment while sparing the peritumoral immune microenvironment

Fig. 4

Induction of the bystander and abscopal effects by time-synchronized immune-guided SBRT-PATHY: Figure shows a very voluminous lymph node metastasis of the left neck in metastatic melanoma patient, with a maximum diameter of 10 × 7 cm before SBRT-PATHY (red arrow, upper image left), as well as one additional lymph node metastasis with a maximum diameter 2 × 2 cm that was not irradiated (red arrow, lower image left). A dramatic regression of the partially treated bulky lesion and also of unirradiated smaller lymph node metastasis was observed 4 weeks later (green arrows, upper and lower images right)

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